Overexpression of the medium‑conductance calcium‑activated potassium channel (SK4) and the HCN2 channel to generate a biological pacemaker.
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DOI: 10.3892/mmr.2019.10591
Abstract: Ion channels serve important roles in the excitation‑contraction coupling of cardiac myocytes. Previous studies have shown that the overexpression or activation of intermediate‑conductance calcium‑activated potassium channel (SK4, encoded by KCNN4) in embryonic stem cell‑derived cardiomyocytes… read more here.
Keywords: hcn2; channel; sk4 hcn2; biological pacemaker ... See more keywords