Articles with "ska 346" as a keyword



The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator

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Published in 2024 at "RSC Advances"

DOI: 10.1039/d4ra07330d

Abstract: The calcium-activated KCa3.1 channel plays a crucial role in T-cell immune response. Genetic manipulation of T-cells to upregulate the expression of K+ channels has been shown to boost T-cell cytotoxicity in cancer. Here, we aimed… read more here.

Keywords: kca3; kca3 channel; activator; ska 346 ... See more keywords