Dephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental cell"
DOI: 10.1016/j.devcel.2017.04.013
Abstract: During cell division, genome inheritance is orchestrated by microtubule attachments formed at kinetochores of mitotic chromosomes. The primary microtubule coupler at the kinetochore, the Ndc80 complex, is regulated by Aurora kinase phosphorylation of its N-terminal… read more here.
Keywords: kinetochore microtubule; ndc80 tail; microtubule attachments; tail ... See more keywords
The stress response HPA-axis hormone, glucocorticoid, reduces cellular SKA complex gene expression
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DOI: 10.1016/j.psychres.2017.12.024
Abstract: The Spindle- and Kinetochore-Associated (SKA) complex has been proven to be involved in many human mental behavioral disorders. Glucocorticoid, a hypothalamic-pituitary-adrenal (HPA) axis hormone, is a critical mediator of stress response in neurons. However, the… read more here.
Keywords: ska; axis hormone; ska complex; hpa axis ... See more keywords
Transcript levels of spindle and kinetochore-associated complex 1/3 as prognostic biomarkers correlated with immune infiltrates in hepatocellular carcinoma
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DOI: 10.1038/s41598-021-89628-z
Abstract: The spindle and kinetochore-associated protein complex (Ska) is an essential component in chromosome segregation. It comprises three proteins (Ska1, Ska2, and Ska3) with theorized roles in chromosomal instability and tumor development, and its overexpression has… read more here.
Keywords: hepatocellular carcinoma; spindle kinetochore; expression; ska ... See more keywords