Phosphorylation of small kinetochore-associated protein induced by GSK3β promotes cell migration and invasion in esophageal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2038847
Abstract: ABSTRACT Glycogen synthesis kinase-3β (GSK-3β) is a kinase shown to regulate esophageal cancer (EC) progression. However, the significance of GSK-3β in phosphorylation of small kinetochore-associated protein (SKAP) has not been fully characterized. GSK-3β/SKAP expression was… read more here.
Keywords: skap; invasion; gsk; cell migration ... See more keywords
SKAP interacts with Aurora B to guide end-on capture of spindle microtubules via phase separation.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular cell biology"
DOI: 10.1093/jmcb/mjab058
Abstract: Chromosome segregation in mitosis is orchestrated by the dynamic interactions between the kinetochore and spindle microtubules. Our recent studies show that mitotic motor CENP-E cooperates with SKAP and forms a link between kinetochore core MIS13… read more here.
Keywords: phase separation; end; skap; via phase ... See more keywords