Comprehensive Analysis of the Immune Implication of TEX41 in Skin Cutaneous Melanoma
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DOI: 10.1155/2021/2409820
Abstract: Enhancer RNAs (eRNAs), a subclass of noncoding RNAs from enhancers, have been demonstrated to exhibit important regulatory effects on the expressions of various genes. However, the role of eRNAs in skin cutaneous melanoma (SKCM) remained… read more here.
Keywords: skin cutaneous; skcm; comprehensive analysis; cutaneous melanoma ... See more keywords
The Overexpression of SLC25A13 Predicts Poor Prognosis and Is Correlated with Immune Cell Infiltration in Patients with Skin Cutaneous Melanoma
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DOI: 10.1155/2022/4091978
Abstract: Purpose Skin cutaneous melanoma (SKCM) is one of the most malignant and aggressive cancers with poor prognosis due to its rapid progression towards metastasis. Thus, finding clinically relevant biomarkers for early diagnosis, prognosis, and therapy… read more here.
Keywords: infiltration; prognosis; slc25a13; skin cutaneous ... See more keywords
Construction of Prognostic Risk Model of Patients with Skin Cutaneous Melanoma Based on TCGA-SKCM Methylation Cohort
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/4261329
Abstract: Skin cutaneous melanoma (SKCM) is a common malignant skin cancer. Early diagnosis could effectively reduce SKCM patient's mortality to a large extent. We managed to construct a model to examine the prognosis of SKCM patients.… read more here.
Keywords: methylation; regression; prognosis; model ... See more keywords
TREM2 as a Potential Immune-Related Biomarker of Prognosis in Patients with Skin Cutaneous Melanoma Microenvironment
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DOI: 10.1155/2023/8101837
Abstract: Background The skin cutaneous melanoma (SKCM) is a devastating form of skin cancer triggered by genetic and environmental factors, and the incidence of SKCM has rapidly increased in recent years. Immune infiltration of the tumor… read more here.
Keywords: trem2; trem2 expression; expression; level trem2 ... See more keywords
Correlation of CCL8 expression with immune cell infiltration of skin cutaneous melanoma: potential as a prognostic indicator and therapeutic pathway
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Cell International"
DOI: 10.1186/s12935-021-02350-8
Abstract: Background The tumor microenvironment (TME) is critical in the progression and metastasis of skin cutaneous melanoma (SKCM). Differences in tumor-infiltrating immune cells (TICs) and their gene expression have been linked to cancer prognosis. Given that… read more here.
Keywords: expression; potential prognostic; cutaneous melanoma; skin cutaneous ... See more keywords
Prognostic and immune-related value of STK17B in skin cutaneous melanoma
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DOI: 10.1371/journal.pone.0263311
Abstract: Skin cutaneous melanoma (SKCM) is a common cancer of which mortality is increasing continuously. Our study conducted a series of analyses on the clinical significance of Serine/threonine kinase 17B (STK17B) in SKCM to provide a… read more here.
Keywords: melanoma; expression; skin cutaneous; immune ... See more keywords
USP35 is a Potential Immunosuppressive Factor in Skin Cutaneous Melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s362619
Abstract: Background As one of the most immunogenic malignancies, skin cutaneous melanoma (SKCM) is mainly characterized by a high prevalence in immune-compromised patients and a brisk lymphocyte infiltration in the tumor microenvironment (TME). However, to date,… read more here.
Keywords: skin cutaneous; potential immunosuppressive; usp35 potential; cutaneous melanoma ... See more keywords
The Identification of the Metabolism Subtypes of Skin Cutaneous Melanoma Associated With the Tumor Microenvironment and the Immunotherapy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.707677
Abstract: Skin cutaneous melanoma (SKCM) is a highly aggressive and resistant cancer with immense metabolic heterogeneity. Here, we performed a comprehensive examination of the diverse metabolic signatures of SKCM based on non-negative matrix factorization (NMF) categorization,… read more here.
Keywords: immunotherapy; skin cutaneous; skcm; metabolic activity ... See more keywords
Prognostic and immune-related value of complement C1Q (C1QA, C1QB, and C1QC) in skin cutaneous melanoma
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DOI: 10.3389/fgene.2022.940306
Abstract: Background: Skin cutaneous melanoma (SKCM) is a common malignancy that is associated with increased morbidity and mortality. Complement C1Q is composed of C1QA, C1QB, and C1QC and is involved in the occurrence and development of… read more here.
Keywords: skcm; c1qa c1qb; expression; c1qb c1qc ... See more keywords
Anti-proliferative and pro-apoptotic effects of curcumin on skin cutaneous melanoma: Bioinformatics analysis and in vitro experimental studies
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DOI: 10.3389/fgene.2022.983943
Abstract: Objective: To reveal the potential mechanisms of curcumin for the treatment of skin cutaneous melanoma (SKCM) and its identify novel prognostic biomarkers. Methods: We searched the Cancer Genome Atlas and Traditional Chinese Medicine Systems Pharmacology… read more here.
Keywords: curcumin; skin cutaneous; analysis; cutaneous melanoma ... See more keywords
A new ferroptosis-related genetic mutation risk model predicts the prognosis of skin cutaneous melanoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.988909
Abstract: Background: Ferroptosis is an iron-dependent cell death mode and closely linked to various cancers, including skin cutaneous melanoma (SKCM). Although attempts have been made to construct ferroptosis-related gene (FRG) signatures for predicting the prognosis of… read more here.
Keywords: related genetic; ferroptosis related; ferrgr; model ... See more keywords