Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone-derived IGF-1 secretion.
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DOI: 10.1111/cpr.13476
Abstract: Senile osteoporosis is characterized by age-related bone loss and bone microarchitecture deterioration. However, little is known to date about the mechanism that maintains bone homeostasis during aging. In this study, we identify adenosine monophosphate-activated protein… read more here.
Keywords: igf secretion; bone; promoting bone; skeletal aging ... See more keywords