CaMKK2 Signaling in Metabolism and Skeletal Disease: a New Axis with Therapeutic Potential
Sign Up to like & getrecommendations! Published in 2019 at "Current Osteoporosis Reports"
DOI: 10.1007/s11914-019-00518-w
Abstract: Purpose of ReviewAge and metabolic disorders result in the accumulation of advanced glycation endproducts (AGEs), oxidative stress, and inflammation, which cumulatively cause a decline in skeletal health. Bone becomes increasingly vulnerable to fractures and its… read more here.
Keywords: metabolism; signaling metabolism; camkk2 signaling; camkk2 ... See more keywords
Using mouse genetics to understand human skeletal disease.
Sign Up to like & getrecommendations! Published in 2019 at "Bone"
DOI: 10.1016/j.bone.2019.02.015
Abstract: Technological advances have enabled the study of the human genome in incredible detail with relative ease. However, our ability to interpret the functional significance of the millions of genetic variants present within each individual is… read more here.
Keywords: genetics; using mouse; mouse genetics; skeletal disease ... See more keywords