Articles with "skeletal myofibers" as a keyword



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Mislocalization of SMN from the I-band and M-band in human skeletal myofibers in spinal muscular atrophy associates with primary structural alterations of the sarcomere

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Published in 2020 at "Cell and Tissue Research"

DOI: 10.1007/s00441-020-03236-3

Abstract: Spinal muscular atrophy (SMA) is caused by a deletion or mutation of the survival motor neuron 1 (SMN1) gene. Reduced SMN levels lead to motor neuron degeneration and muscular atrophy. SMN protein localizes to the… read more here.

Keywords: skeletal myofibers; smn; spinal muscular; band ... See more keywords
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Deletion of Pofut1 in Mouse Skeletal Myofibers Induces Muscle Aging-Related Phenotypes in cis and in trans

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Published in 2017 at "Molecular and Cellular Biology"

DOI: 10.1128/mcb.00426-16

Abstract: ABSTRACT Sarcopenia, the loss of muscle mass and strength during normal aging, involves coordinate changes in skeletal myofibers and the cells that contact them, including satellite cells and motor neurons. Here we show that the… read more here.

Keywords: skeletal myofibers; muscle; related phenotypes; aging related ... See more keywords
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Skeletal Muscle Atrophy Induced by Diabetes Is Mediated by Non-Selective Channels and Prevented by Boldine

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Published in 2023 at "Biomolecules"

DOI: 10.3390/biom13040708

Abstract: Individuals with diabetes mellitus present a skeletal muscle myopathy characterized by atrophy. However, the mechanism underlying this muscular alteration remains elusive, which makes it difficult to design a rational treatment that could avoid the negative… read more here.

Keywords: skeletal myofibers; prevented boldine; skeletal muscle; atrophy ... See more keywords