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Published in 2020 at "Cell and Tissue Research"
DOI: 10.1007/s00441-020-03236-3
Abstract: Spinal muscular atrophy (SMA) is caused by a deletion or mutation of the survival motor neuron 1 (SMN1) gene. Reduced SMN levels lead to motor neuron degeneration and muscular atrophy. SMN protein localizes to the…
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Keywords:
skeletal myofibers;
smn;
spinal muscular;
band ... See more keywords
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Published in 2017 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00426-16
Abstract: ABSTRACT Sarcopenia, the loss of muscle mass and strength during normal aging, involves coordinate changes in skeletal myofibers and the cells that contact them, including satellite cells and motor neurons. Here we show that the…
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Keywords:
skeletal myofibers;
muscle;
related phenotypes;
aging related ... See more keywords
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Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13040708
Abstract: Individuals with diabetes mellitus present a skeletal muscle myopathy characterized by atrophy. However, the mechanism underlying this muscular alteration remains elusive, which makes it difficult to design a rational treatment that could avoid the negative…
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Keywords:
skeletal myofibers;
prevented boldine;
skeletal muscle;
atrophy ... See more keywords