Utilization of agents to prevent skeletal-related events among patients with multiple myeloma: analysis of real-world data
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DOI: 10.1007/s00520-017-3892-4
Abstract: PurposeThis study examined real-world utilization patterns of bone-targeted agents (BTA) in patients with multiple myeloma (MM).MethodsIn this retrospective cohort study, adults with an MM diagnosis recorded in 2012–2014 were identified from electronic health records in… read more here.
Keywords: real world; skeletal related; multiple myeloma; patients multiple ... See more keywords
Prevention of serious skeletal-related events by interventional radiology techniques in patients with malignant paraganglioma and pheochromocytoma
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DOI: 10.1007/s12020-017-1515-y
Abstract: PurposeBone metastases (BM) and skeletal-related events (SRE) are frequent in patients with malignant pheochromocytoma and paraganglioma (PPM) and the best modality of prevention unknown. The role of interventional radiology (IR) techniques for the prevention of… read more here.
Keywords: interventional radiology; skeletal related; patients malignant; radiology ... See more keywords
Discharge status and post-discharge healthcare costs after skeletal-related event hospitalizations among medicare patients with bone metastatic solid tumors or multiple myeloma
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DOI: 10.1016/j.jbo.2020.100328
Abstract: Highlights • Most elderly cancer patients (>75%) require healthcare facility support after skeletal-related event-related hospitalization, with substantial associated costs.• The largest proportion of bone metastases patients were discharged to skilled nursing facilities (SNF) (32.9%), then… read more here.
Keywords: skeletal related; related event; discharge; multiple myeloma ... See more keywords
Experience with denosumab (XGEVA®) for prevention of skeletal-related events in the 10 years after approval
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DOI: 10.1016/j.jbo.2022.100416
Abstract: Highlights • Skeletal-related events (SRE) with tumors have significant patient/economic burden.• Denosumab (RANKL inhibitor) is approved for SRE prevention in MM and solid tumor BM.• Denosumab reduced risk of first/subsequent SREs versus zoledronate in solid… read more here.
Keywords: skeletal related; experience denosumab; related events; prevention ... See more keywords
Economic burden of skeletal-related events in patients with multiple myeloma: analysis of US commercial claims database
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DOI: 10.1080/13696998.2018.1457531
Abstract: Abstract Aims: To estimate incremental healthcare resource utilization (HRU) and costs associated with skeletal-related events (SREs) secondary to multiple myeloma (MM), and HRU and cost differences in patients with one vs multiple SREs. Methods: Adults… read more here.
Keywords: index; skeletal related; multiple myeloma; patients multiple ... See more keywords
Health resource utilisation associated with skeletal‐related events in patients with bone metastases secondary to solid tumours: regional comparisons in an observational study
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DOI: 10.1111/ecc.12452
Abstract: &NA; Skeletal‐related events (SREs) including spinal cord compression, pathologic fracture, and radiation or surgery to bone, occur frequently due to bone metastases in advanced cancer. This analysis of a multicentre, observational study was designed to… read more here.
Keywords: bone metastases; resource utilisation; observational study; skeletal related ... See more keywords
Healthcare resource utilisation associated with skeletal‐related events in European patients with multiple myeloma: Results from a prospective, multinational, observational study
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DOI: 10.1111/ejh.13044
Abstract: Patients with multiple myeloma (MM) often experience debilitating skeletal‐related events (SREs: pathologic fracture, radiation to bone [RB], surgery to bone [SB] or spinal cord compression [SCC]). This is the first comprehensive, prospective, observational analysis of… read more here.
Keywords: resource utilisation; healthcare resource; skeletal related; multiple myeloma ... See more keywords
Incidence of skeletal related events in patients with bone metastasis receiving denosumab every four weeks compared to intervals greater than every four weeks
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DOI: 10.1177/1078155217743074
Abstract: Objective Denosumab is a monoclonal antibody used for prevention of skeletal related events in patients with bone metastasis from solid tumors and is administered every four weeks. In our practice, denosumab is often given at… read more here.
Keywords: skeletal related; every four; incidence skeletal; related events ... See more keywords
Clinicopathologic characteristics, metastasis-free survival, and skeletal-related events in 628 patients with skeletal metastases in a tertiary orthopedic and trauma center
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DOI: 10.1186/s12957-021-02169-7
Abstract: Background Skeletal-related events (SREs) due to bone metastases (BM) significantly impact the morbidity and mortality of cancer patients. The present study sought to investigate clinicopathological characteristics, metastasis-free survival (MFS), and SREs in patients referred to… read more here.
Keywords: metastasis free; skeletal related; characteristics metastasis; free survival ... See more keywords
Adherence and cumulative bisphosphonate dose in relation to risk of skeletal-related events among older patients with multiple myeloma.
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DOI: 10.1200/jco.2019.37.15_suppl.e18250
Abstract: e18250 Background: Adjuvant intravenous bisphosphonates (IV BP) reduce the risk of skeletal-related events (SRE) in patients with multiple myeloma (MM). We examined the effects of bisphosphonate utilization patterns (adherence, cumulative dose and frequency) on risk… read more here.
Keywords: dose; risk; adherence; skeletal related ... See more keywords
Association of radical cystectomy and increased risk of skeletal-related events in bone-metastatic urothelial carcinoma.
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DOI: 10.1200/jco.2020.38.6_suppl.477
Abstract: 477Background: Bone metastases are common in patients with advanced cancer of the bladder or upper urinary tract; however, few studies have assessed the morbidity of bone metastases in these patien... read more here.
Keywords: cystectomy increased; association radical; skeletal related; increased risk ... See more keywords