Size and dielectric properties of skeletal stem cells change critically after enrichment and expansion from human bone marrow: consequences for microfluidic cell sorting
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2017.0233
Abstract: The capacity of bone and cartilage to regenerate can be attributed to skeletal stem cells (SSCs) that reside within the bone marrow (BM). Given SSCs are rare and lack specific surface markers, antibody-based sorting has… read more here.
Keywords: cell; size; stem cells; skeletal stem ... See more keywords
BMPR1A maintains skeletal stem cell properties in craniofacial development and craniosynostosis
Sign Up to like & getrecommendations! Published in 2021 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abb4416
Abstract: Stemness of skeletal stem cells in the calvarium is maintained by BMPR1A; disruption depletes stem cells and causes cranial bone fusion. Signaling and suture stem cells Suture stem cells give rise to craniofacial bone, and… read more here.
Keywords: stem cell; suture stem; stem; stem cells ... See more keywords
Identification of Dental Stem Cells Similar to Skeletal Stem Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Dental Research"
DOI: 10.1177/00220345221084199
Abstract: Stem and progenitor cells play important roles in the development and maintenance of teeth and bone. Surface markers expressed in bone marrow–derived mesenchymal stem cells are also expressed in dental tissue–derived stem cells. Mouse skeletal… read more here.
Keywords: dental stem; cells similar; skeletal stem; stem ... See more keywords
Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice
Sign Up to like & getrecommendations! Published in 2018 at "Biology Open"
DOI: 10.1242/bio.032094
Abstract: ABSTRACT Site-1 protease (S1P) is a proprotein convertase with essential functions in the conversion of precursor proteins to their active form. In earlier studies, we demonstrated that S1P ablation in the chondrocyte lineage results in… read more here.
Keywords: bone; site protease; differentiation; mice ... See more keywords
Niches for Skeletal Stem Cells of Mesenchymal Origin
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00592
Abstract: With very few exceptions, all adult tissues in mammals are maintained and can be renewed by stem cells that self-renew and generate the committed progeny required. These functions are regulated by a specific and in… read more here.
Keywords: cells mesenchymal; niches skeletal; stem cell; stem ... See more keywords
Periosteal Skeletal Stem Cells and Their Response to Bone Injury
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.812094
Abstract: Bone exhibits remarkable self-repair ability without fibrous scars. It is believed that the robust regenerative capacity comes from tissue-resident stem cells, such as skeletal stem cells (SSCs). Roughly, SSC has two niches: bone marrow (BM)… read more here.
Keywords: bone injury; skeletal stem; sscs; stem ... See more keywords
Cellular dynamics of distinct skeletal cells and the development of osteosarcoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1181204
Abstract: Bone contributes to the maintenance of vital biological activities. At the cellular level, multiple types of skeletal cells, including skeletal stem and progenitor cells (SSPCs), osteoblasts, chondrocytes, marrow stromal cells, and adipocytes, orchestrate skeletal events… read more here.
Keywords: skeletal cells; development; bone; skeletal stem ... See more keywords
Aged Callus Skeletal Stem/Progenitor Cells Contain an Inflammatory Osteogenic Population With Increased IRF and NF-κB Pathways and Reduced Osteogenic Potential
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.806528
Abstract: Skeletal stem/progenitor cells (SSPCs) are critical for fracture repair by providing osteo-chondro precursors in the callus, which is impaired in aging. However, the molecular signatures of callus SSPCs during aging are not known. Herein, we… read more here.
Keywords: stem progenitor; skeletal stem; osteogenic population; progenitor cells ... See more keywords
Age-associated declining of the regeneration potential of skeletal stem/progenitor cells
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1087254
Abstract: Bone fractures represent a significant health burden worldwide, mainly because of the rising number of elderly people. As people become older, the risk and the frequency of bone fractures increase drastically. Such increase arises from… read more here.
Keywords: regeneration; potential skeletal; bone; stem progenitor ... See more keywords
Analysis of skeletal stem cells by renal capsule transplantation and ex vivo culture systems
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1143344
Abstract: Skeletal stem cells residing in the suture mesenchyme are responsible for proper development, homeostasis, and injury repair of the craniofacial skeleton. These naïve cells are programmed to differentiate into osteoblast cell types and mediate bone… read more here.
Keywords: culture; stem cell; skeletal stem; stem ... See more keywords