Mining database for the expression and gene regulation network of JAK2 in skin cutaneous melanoma.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117600
Abstract: BACKGROUND Skin cutaneous melanoma (SKCM) is the most common subtype of skin malignancy, with ever-increasing incidence, mortality, and disease burden. Dysregulation of JAK-STATs signaling pathway is involved in the pathogenesis and progression of cancers, thus… read more here.
Keywords: gene regulation; skin cutaneous; cutaneous melanoma; expression ... See more keywords
PAPPA2 mutation as a novel indicator stratifying beneficiaries of immune checkpoint inhibitors in skin cutaneous melanoma and non‐small cell lung cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cell Proliferation"
DOI: 10.1111/cpr.13283
Abstract: Pappalysin 2 (PAPPA2) mutation, occurring most frequently in skin cutaneous melanoma (SKCM) and non‐small cell lung cancer (NSCLC), is found to be related to anti‐tumour immune response. However, the association between PAPPA2 and the efficacy… read more here.
Keywords: cell; non small; pappa2 mutation; pappa2 ... See more keywords
Comprehensive Analysis of the Immune Implication of TEX41 in Skin Cutaneous Melanoma
Sign Up to like & getrecommendations! Published in 2021 at "Disease Markers"
DOI: 10.1155/2021/2409820
Abstract: Enhancer RNAs (eRNAs), a subclass of noncoding RNAs from enhancers, have been demonstrated to exhibit important regulatory effects on the expressions of various genes. However, the role of eRNAs in skin cutaneous melanoma (SKCM) remained… read more here.
Keywords: skin cutaneous; skcm; comprehensive analysis; cutaneous melanoma ... See more keywords
Long Noncoding RNA LINC02249 Is a Prognostic Biomarker and Correlates with Immunosuppressive Microenvironment in Skin Cutaneous Melanoma
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DOI: 10.1155/2022/2054901
Abstract: Skin cutaneous melanoma (SKCM) is one of the most aggressive and life-threatening tumors. It has a high incidence rate, as well as significant metastasis and fatality rates. To successfully treat SKCM and to increase the… read more here.
Keywords: linc02249; long noncoding; expression; skin cutaneous ... See more keywords
The Overexpression of SLC25A13 Predicts Poor Prognosis and Is Correlated with Immune Cell Infiltration in Patients with Skin Cutaneous Melanoma
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DOI: 10.1155/2022/4091978
Abstract: Purpose Skin cutaneous melanoma (SKCM) is one of the most malignant and aggressive cancers with poor prognosis due to its rapid progression towards metastasis. Thus, finding clinically relevant biomarkers for early diagnosis, prognosis, and therapy… read more here.
Keywords: infiltration; prognosis; slc25a13; skin cutaneous ... See more keywords
Screening of gene markers related to the prognosis of metastatic skin cutaneous melanoma based on Logit regression and survival analysis
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DOI: 10.1186/s12920-021-00923-0
Abstract: Background Bioinformatics was used to analyze the skin cutaneous melanoma (SKCM) gene expression profile to provide a theoretical basis for further studying the mechanism underlying metastatic SKCM and the clinical prognosis. Methods We downloaded the… read more here.
Keywords: logit regression; skin cutaneous; prognosis; cutaneous melanoma ... See more keywords
Correlation of CCL8 expression with immune cell infiltration of skin cutaneous melanoma: potential as a prognostic indicator and therapeutic pathway
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Cell International"
DOI: 10.1186/s12935-021-02350-8
Abstract: Background The tumor microenvironment (TME) is critical in the progression and metastasis of skin cutaneous melanoma (SKCM). Differences in tumor-infiltrating immune cells (TICs) and their gene expression have been linked to cancer prognosis. Given that… read more here.
Keywords: expression; potential prognostic; cutaneous melanoma; skin cutaneous ... See more keywords
Prognostic and immune-related value of STK17B in skin cutaneous melanoma
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DOI: 10.1371/journal.pone.0263311
Abstract: Skin cutaneous melanoma (SKCM) is a common cancer of which mortality is increasing continuously. Our study conducted a series of analyses on the clinical significance of Serine/threonine kinase 17B (STK17B) in SKCM to provide a… read more here.
Keywords: melanoma; expression; skin cutaneous; immune ... See more keywords
Skin cutaneous melanoma properties of immune-related lncRNAs identifying potential prognostic biomarkers.
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DOI: 10.18632/aging.203982
Abstract: Skin cutaneous melanoma (SKCM) is one of the most aggressive and life-threatening cancers with high incidence rate, metastasis rate and mortality. Early detection and stratification of risk assessment are essential to treat SKCM and to… read more here.
Keywords: risk; related lncrnas; immune related; cutaneous melanoma ... See more keywords
Characterization of m6A-Related Genes Landscape in Skin Cutaneous Melanoma to Aid Immunotherapy and Assess Prognosis
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s328522
Abstract: Background Skin cutaneous melanoma (SKCM) is the most malignant tumor among skin cancers. Immunotherapy has shown a great role in the advantageous prognosis of SKCM. However, only a small percentage of people can benefit from… read more here.
Keywords: cutaneous melanoma; m6a scores; immunotherapy; prognosis ... See more keywords
USP35 is a Potential Immunosuppressive Factor in Skin Cutaneous Melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s362619
Abstract: Background As one of the most immunogenic malignancies, skin cutaneous melanoma (SKCM) is mainly characterized by a high prevalence in immune-compromised patients and a brisk lymphocyte infiltration in the tumor microenvironment (TME). However, to date,… read more here.
Keywords: skin cutaneous; potential immunosuppressive; usp35 potential; cutaneous melanoma ... See more keywords