Mining database for the expression and gene regulation network of JAK2 in skin cutaneous melanoma.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117600
Abstract: BACKGROUND Skin cutaneous melanoma (SKCM) is the most common subtype of skin malignancy, with ever-increasing incidence, mortality, and disease burden. Dysregulation of JAK-STATs signaling pathway is involved in the pathogenesis and progression of cancers, thus… read more here.
Keywords: gene regulation; skin cutaneous; cutaneous melanoma; expression ... See more keywords
Matrix metalloproteinases as diagnostic and prognostic biomarkers in skin cutaneous melanoma and squamous cell carcinoma
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DOI: 10.1038/s41598-025-06608-3
Abstract: Skin cutaneous melanoma (SKCM) and squamous cell carcinoma (SCC) are two prevalent forms of skin cancer, both characterized by extensive remodeling of the extracellular matrix (ECM), which facilitates tumor progression and metastasis. To investigate ECM-related… read more here.
Keywords: matrix metalloproteinases; diagnostic prognostic; cutaneous melanoma; squamous cell ... See more keywords
Targeting LAG3 to alter the tumor immune reactivity of CD8+T cells is a potential therapy for skin cutaneous melanoma
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DOI: 10.1038/s41598-025-22377-5
Abstract: CD8+ T cells exert a significant effect in immune infiltration, drug resistance and cell survival in cancers, but the roles and mechanisms in skin cutaneous melanoma (SKCM) remain unclear. In the present study, prognostic biomarkers… read more here.
Keywords: cd8 cells; cd8; melanoma; cell ... See more keywords
PAPPA2 mutation as a novel indicator stratifying beneficiaries of immune checkpoint inhibitors in skin cutaneous melanoma and non‐small cell lung cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cell Proliferation"
DOI: 10.1111/cpr.13283
Abstract: Pappalysin 2 (PAPPA2) mutation, occurring most frequently in skin cutaneous melanoma (SKCM) and non‐small cell lung cancer (NSCLC), is found to be related to anti‐tumour immune response. However, the association between PAPPA2 and the efficacy… read more here.
Keywords: cell; non small; pappa2 mutation; pappa2 ... See more keywords
Characteristics and significance of programmed cell death‐related gene expression signature in skin cutaneous melanoma
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DOI: 10.1111/srt.13739
Abstract: Programmed cell death (PCD) pathways play crucial roles in the pathogenesis of skin cutaneous melanoma (SKCM). Understanding their prognostic significance and clinical implications is imperative for the development of personalized treatment strategies. read more here.
Keywords: skin cutaneous; cutaneous melanoma; cell death; programmed cell ... See more keywords
Comprehensive Analysis of the Immune Implication of TEX41 in Skin Cutaneous Melanoma
Sign Up to like & getrecommendations! Published in 2021 at "Disease Markers"
DOI: 10.1155/2021/2409820
Abstract: Enhancer RNAs (eRNAs), a subclass of noncoding RNAs from enhancers, have been demonstrated to exhibit important regulatory effects on the expressions of various genes. However, the role of eRNAs in skin cutaneous melanoma (SKCM) remained… read more here.
Keywords: skin cutaneous; skcm; comprehensive analysis; cutaneous melanoma ... See more keywords
Long Noncoding RNA LINC02249 Is a Prognostic Biomarker and Correlates with Immunosuppressive Microenvironment in Skin Cutaneous Melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/2054901
Abstract: Skin cutaneous melanoma (SKCM) is one of the most aggressive and life-threatening tumors. It has a high incidence rate, as well as significant metastasis and fatality rates. To successfully treat SKCM and to increase the… read more here.
Keywords: linc02249; long noncoding; expression; skin cutaneous ... See more keywords
The Overexpression of SLC25A13 Predicts Poor Prognosis and Is Correlated with Immune Cell Infiltration in Patients with Skin Cutaneous Melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/4091978
Abstract: Purpose Skin cutaneous melanoma (SKCM) is one of the most malignant and aggressive cancers with poor prognosis due to its rapid progression towards metastasis. Thus, finding clinically relevant biomarkers for early diagnosis, prognosis, and therapy… read more here.
Keywords: infiltration; prognosis; slc25a13; skin cutaneous ... See more keywords
Screening of gene markers related to the prognosis of metastatic skin cutaneous melanoma based on Logit regression and survival analysis
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DOI: 10.1186/s12920-021-00923-0
Abstract: Background Bioinformatics was used to analyze the skin cutaneous melanoma (SKCM) gene expression profile to provide a theoretical basis for further studying the mechanism underlying metastatic SKCM and the clinical prognosis. Methods We downloaded the… read more here.
Keywords: logit regression; skin cutaneous; prognosis; cutaneous melanoma ... See more keywords
Correlation of CCL8 expression with immune cell infiltration of skin cutaneous melanoma: potential as a prognostic indicator and therapeutic pathway
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Cell International"
DOI: 10.1186/s12935-021-02350-8
Abstract: Background The tumor microenvironment (TME) is critical in the progression and metastasis of skin cutaneous melanoma (SKCM). Differences in tumor-infiltrating immune cells (TICs) and their gene expression have been linked to cancer prognosis. Given that… read more here.
Keywords: expression; potential prognostic; cutaneous melanoma; skin cutaneous ... See more keywords
Prognostic and immune-related value of STK17B in skin cutaneous melanoma
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DOI: 10.1371/journal.pone.0263311
Abstract: Skin cutaneous melanoma (SKCM) is a common cancer of which mortality is increasing continuously. Our study conducted a series of analyses on the clinical significance of Serine/threonine kinase 17B (STK17B) in SKCM to provide a… read more here.
Keywords: melanoma; expression; skin cutaneous; immune ... See more keywords