Dendritic Cell Migration to Skin-Draining Lymph Nodes Is Controlled by Dermatan Sulfate and Determines Adaptive Immunity Magnitude
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DOI: 10.3389/fimmu.2018.00206
Abstract: For full activation of naïve adaptive lymphocytes in skin-draining lymph nodes (LNs), presentation of peptide:MHC complexes by LN-resident and skin-derived dendritic cells (DCs) that encountered antigens (Ags) is an absolute prerequisite. To get to the… read more here.
Keywords: draining lymph; lymph nodes; migration; adaptive immunity ... See more keywords
Exposure to solar ultraviolet radiation establishes a novel immune suppressive lipidome in skin-draining lymph nodes
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1045731
Abstract: The ability of ultraviolet radiation to suppress the immune system is thought to be central to both its beneficial (protection from autoimmunity) and detrimental (carcinogenic) effects. Previous work revealed a key role for lipids particularly… read more here.
Keywords: draining lymph; ultraviolet radiation; skin draining; immune suppressive ... See more keywords