Articles with "skin fibroblast" as a keyword



Autologous Skin Fibroblast‐Based PLGA Nanoparticles for Treating Multiorgan Fibrosis

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Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202200856

Abstract: Fibrotic diseases remain a substantial health burden with few therapeutic approaches. A hallmark of fibrosis is the aberrant activation and accumulation of myofibroblasts, which is caused by excessive profibrotic cytokines. Conventional anticytokine therapies fail to… read more here.

Keywords: autologous skin; skin; skin fibroblast; fibrosis ... See more keywords

Hydrogen Sulfide Suppresses Skin Fibroblast Proliferation via Oxidative Stress Alleviation and Necroptosis Inhibition

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/7434733

Abstract: Keloid is a common dermatofibrotic disease with excessive skin fibroblast proliferation. Hydrogen sulfide (H2S) as the third gasotransmitter improves fibrosis of various organs and tissues. Our study is aimed at investigating the effects and possible… read more here.

Keywords: proliferation via; via oxidative; skin fibroblast; fibroblast proliferation ... See more keywords

Next-generation sequencing (NGS) of DNA isolated from nail specimens and run in parallel with tumor NGS accurately and efficiently detects germline predisposition variants in myeloid malignancies

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Published in 2025 at "Blood"

DOI: 10.1182/blood-2025-1084

Abstract: Background: Germline predisposition occurs in patients of all ages with myeloid malignancies and is important to identify due to implications for family members and donor selection for stem cell transplant. The gold standard method of… read more here.

Keywords: germline; history; nail specimens; germline testing ... See more keywords

Overexpression of miR-340-5p inhibits skin fibroblast proliferation by targeting Kruppel-like factor 2.

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Published in 2019 at "Current pharmaceutical biotechnology"

DOI: 10.2174/1389201020666190725112304

Abstract: OBJECTIVE MicroRNA (miR)-340-5p has been identified to play a key role in several cancers. However, the function of miR-340-5p in skin fibroblasts remains largely unknown. METHOD Gain of function was used by infecting the normal… read more here.

Keywords: overexpression; ontology; skin fibroblast; fibroblast proliferation ... See more keywords

Direct T-2 Toxicity on Human Skin—Fibroblast Hs68 Cell Line—In Vitro Study

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23094929

Abstract: T-2 toxin is produced by different Fusarium species, and it can infect crops such as wheat, barley, and corn. It is known that the T-2 toxin induces various forms of toxicity such as hepatotoxicity, nephrotoxicity,… read more here.

Keywords: cell line; toxicity; toxin; human skin ... See more keywords