Lysyl oxidase activity in human skin is increased by chronic ultraviolet radiation exposure and smoking
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Dermatology"
DOI: 10.1111/bjd.14959
Abstract: Lifestyle choices, such as tobacco smoking and sunbathing can lead to premature skin ageing1. These extrinsic accelerators of the ageing process cause profound changes to the abundance and arrangement of the elastic fibres and fibrillar… read more here.
Keywords: increased chronic; human skin; oxidase activity; lysyl oxidase ... See more keywords
Mitochondrial dysfunction in affected skin and increased mitochondrial DNA in serum from patients with psoriasis
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Dermatology"
DOI: 10.1111/exd.13831
Abstract: Psoriasis is characterized by keratinocyte proliferation and chronic inflammation, but the pathogenesis is still unclear. Dysregulated mitochondria (mt) could lead to reduced apoptosis and extracellular secretion of mtDNA, acting as “innate pathogen” triggering inflammation. Serum… read more here.
Keywords: psoriatic patients; skin; serum; mitochondrial dna ... See more keywords