Monitoring UV‐induced signalling pathways in an ex vivo skin organ culture model using phospho‐antibody array
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13440
Abstract: We investigated UV‐induced signalling in an ex vivo skin organ culture model using phospho‐antibody array. Phosphorylation modulations were analysed in time‐course experiments following exposure to solar‐simulated UV and validated by Western blot analyses. We found… read more here.
Keywords: phospho antibody; vivo skin; skin organ; culture model ... See more keywords
Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.997387
Abstract: Pemphigus is a chronic autoimmune skin blistering disease, characterized by acantholysis and by the production of autoantibodies directed against the structural desmosomal proteins desmoglein 1 (DSG1) and/or DSG3. Model systems allow the identification and testing… read more here.
Keywords: skin organ; skin; microscopy; human skin ... See more keywords
Kinetic Cytokine Secretion Profile of LPS-Induced Inflammation in the Human Skin Organ Culture
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DOI: 10.3390/pharmaceutics12040299
Abstract: Several in vitro models that mimic different aspects of local skin inflammation exist. The use of ex vivo human skin organ culture (HSOC) has been reported previously. However, comprehensive evaluation of the cytokine secretory capacity… read more here.
Keywords: cytokine; secretion; skin organ; cytokine secretion ... See more keywords