Penetration monitoring of drugs and additives by ATR‐FTIR spectroscopy/tape stripping and confocal Raman spectroscopy – A comparative study
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.07.007
Abstract: ABSTRACT Vibrational spectroscopy is a useful tool for analysis of skin properties and to confirm the penetration of drugs and other formulation compounds into the skin. In particular, attenuated total reflection Fourier transform infrared (ATR‐FTIR)… read more here.
Keywords: ftir spectroscopy; penetration; tape stripping; spectroscopy ... See more keywords
Sponge like microparticles for drug delivery and cosmeto-textile use: Formulation and human skin penetration.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.08.122
Abstract: This unique work is targeted to achieve three main goals: i) to enhance the aqueous solubility of three specifically selected hydrophobic active agents, ii) to prepare such polymeric biodegradable microparticles which can encapsulate actives-cyclodextrin complexes… read more here.
Keywords: cyclodextrin; skin penetration; formulation; textile ... See more keywords
Nanoscale investigation of human skin and study of skin penetration of Janus nanoparticles.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119193
Abstract: Janus nanoparticles (JNP) are innovative nanocarriers with an interesting pharmaceutical and cosmetic potential. They are characterized by the presence of a lipid compartment associated with an aqueous compartment delimited by a phospholipid bilayer containing phospholipids… read more here.
Keywords: jnp; skin penetration; human skin; janus nanoparticles ... See more keywords
Skin Penetration Enhancer-Incorporated Lipid Nanovesicles (SPE-LNV) for Skin Brightening and Wrinkle Treatment.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c07135
Abstract: In this work, we utilize skin penetration enhancers (SPEs) such as ceramide and fatty acids in lipid nanovesicles to promote the transdermal delivery of active ingredients. These SPE-incorporated lipid nanovesicles (SPE-LNV) interact with the constituents… read more here.
Keywords: lipid nanovesicles; skin penetration; spe lnv; nanovesicles spe ... See more keywords
Stratum corneum lipid liposomes for investigating skin penetration enhancer effects
Sign Up to like & getrecommendations! Published in 2018 at "RSC Advances"
DOI: 10.1039/c8ra04129f
Abstract: Knowledge of the mechanism of action of skin penetration enhancers is essential to formulators for optimizing formulations and to maximize the efficacy of enhancers. To obtain information about the effects of penetration enhancers as a… read more here.
Keywords: stratum corneum; penetration; lipid liposomes; penetration enhancers ... See more keywords
Skin penetration and tissue permeation after topical administration of diclofenac
Sign Up to like & getrecommendations! Published in 2017 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2017.1352497
Abstract: Abstract Objective: Topical delivery of drugs is an alternative to oral administration, often with similar efficacy but potentially a more favorable tolerability profile. However, topical formulations need to be able to penetrate the skin and… read more here.
Keywords: administration; topical administration; diclofenac; penetration tissue ... See more keywords
Improved stability and skin penetration through glycethosomes loaded with glycyrrhetinic acid
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cosmetic Science"
DOI: 10.1111/ics.12771
Abstract: In recent years, glycyrrhetinic acid (GA) has been popularly used in cosmetics because of its anti‐inflammatory and anti‐oxidant effects. However, due to the poor water solubility of GA and the barrier effect of human skin,… read more here.
Keywords: skin; improved stability; penetration; glycyrrhetinic acid ... See more keywords
The role of viscosity on skin penetration from cellulose ether‐based hydrogels
Sign Up to like & getrecommendations! Published in 2019 at "Skin Research and Technology"
DOI: 10.1111/srt.12709
Abstract: The rheological properties of dermal drug delivery systems are of importance when designing new formulations. Viscosity not only affects features such as spreadability and skin feel, but may also affect the skin penetration of incorporated… read more here.
Keywords: penetration cellulose; viscosity; penetration; role viscosity ... See more keywords
Development and Evaluation of Astaxanthin as Nanostructure Lipid Carriers in Topical Delivery.
Sign Up to like & getrecommendations! Published in 2020 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-020-01822-w
Abstract: The study is designed to formulate, optimize, and evaluate astaxanthin (ASTA)-loaded nanostructured lipid carrier (NLC) with an aim to improve its stability, water solubility, skin permeability and retention and reduce drug-related side effects. ASTA was… read more here.
Keywords: evaluation astaxanthin; drug; skin penetration; development evaluation ... See more keywords
Sorbitan Monolaurate–Containing Liposomes Enhance Skin Cancer Cell Cytotoxicity and in Association with Microneedling Increase the Skin Penetration of 5-Fluorouracil
Sign Up to like & getrecommendations! Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02356-z
Abstract: Squamous cell carcinoma (SCC) represents 20% of cases of non-melanoma skin cancer, and the most common treatment is the removal of the tumor, which can leave large scars. 5-Fluorouracil (5FU) is a drug used in… read more here.
Keywords: cell; cytotoxicity; penetration; skin cancer ... See more keywords
Label-free skin penetration analysis using time-resolved, phase-modulated stimulated Raman scattering microscopy.
Sign Up to like & getrecommendations! Published in 2021 at "Biomedical optics express"
DOI: 10.1364/boe.436142
Abstract: Skin penetration analysis of topically applied drugs or active compounds is essential in biomedical applications. Stimulated Raman scattering (SRS) microscopy is a promising label-free skin penetration analysis tool. However, conventional SRS microcopy suffers from limited… read more here.
Keywords: penetration analysis; skin penetration; microscopy;