Inaccuracy of pulse oximetry with dark skin pigmentation: clinical implications and need for improvement.
Sign Up to like & getrecommendations! Published in 2022 at "British journal of anaesthesia"
DOI: 10.1016/j.bja.2022.03.011
Abstract: Recent reports highlight potential inaccuracies of pulse oximetry in patients with various degrees of skin pigmentation. We summarise the literature, provide an overview of potential clinical implications, and provide insights into how pulse oximetry could… read more here.
Keywords: inaccuracy pulse; pulse oximetry; clinical implications; skin pigmentation ... See more keywords
Classification of non-tumorous skin pigmentation disorders using voting based probabilistic linear discriminant analysis
Sign Up to like & getrecommendations! Published in 2018 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2018.05.026
Abstract: Non-tumorous skin pigmentation disorders can have a huge negative emotional impact on patients. The correct diagnosis of these disorders is essential for proper treatments to be instituted. In this paper, we present a computerized method… read more here.
Keywords: skin pigmentation; pigmentation; pigmentation disorders; non tumorous ... See more keywords
MC1R Peptide Agonist Self-Assembles into a Hydrogel That Promotes Skin Pigmentation for Treating Vitiligo.
Sign Up to like & getrecommendations! Published in 2023 at "ACS nano"
DOI: 10.1021/acsnano.3c01960
Abstract: Vitiligo, a common skin disease that seriously affects 0.5-2.0% of the worldwide population, lacks approved therapeutics due to a wide range of adverse side effects. As a key regulator of skin pigmentation, MC1R may be… read more here.
Keywords: peptide agonist; self assembles; mc1r peptide; skin pigmentation ... See more keywords
A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-018-08147-0
Abstract: We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of skin and eyes. We found eighteen signals of association at twelve genomic regions. These include one novel locus for skin pigmentation (in… read more here.
Keywords: latin americans; skin pigmentation; association; gwas latin ... See more keywords
Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16738-z
Abstract: Tissue homeostasis requires regulation of cell–cell communication, which relies on signaling molecules and cell contacts. In skin epidermis, keratinocytes secrete factors transduced by melanocytes into signaling cues promoting their pigmentation and dendrite outgrowth, while melanocytes… read more here.
Keywords: caveolae; coupling melanocyte; skin pigmentation; pigmentation ... See more keywords
Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations
Sign Up to like & getrecommendations! Published in 2020 at "Communications Biology"
DOI: 10.1038/s42003-020-01461-8
Abstract: Although cutaneous squamous cell carcinoma (cSCC) is one of the most common malignancies in individuals of European ancestry, the incidence of cSCC in Hispanic/Latinos is also increasing. cSCC has both a genetic and environmental etiology.… read more here.
Keywords: risk; skin pigmentation; non hispanic; ancestry ... See more keywords
Skin Pigmentation and Risk of Hearing Loss in Women
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Epidemiology"
DOI: 10.1093/aje/kwx024
Abstract: Black individuals have a lower risk of hearing loss than do whites, possibly because of differences in cochlear melanocytes. Previous studies have suggested that darker-skinned individuals tend to have more inner ear melanin, and cochlear… read more here.
Keywords: hearing loss; risk; risk hearing; skin pigmentation ... See more keywords
TRPA1 promotes UVB‐induced skin pigmentation by regulating melanosome luminal pH
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Dermatology"
DOI: 10.1111/exd.14693
Abstract: Melanocytes stimulated by ultraviolet radiation (UVR) produce melanin and melanosomes, which causes skin pigmentation and acts as an important physiological defence process for photoprotection. Neutral luminal pH of melanosomes is critical for providing optimal conditions… read more here.
Keywords: trpa1; uvb induced; skin pigmentation; induced skin ... See more keywords
Assessment of skin pigmentation by confocal microscopy: Influence of solar exposure and protection habits on cutaneous hyperchromias
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.12307
Abstract: Cutaneous hyperchromias are disorders of skin pigmentation involving an increase of melanin production and its irregular accumulation in skin cells. It is known that the use of sunscreens helps to prevent changes in the skin… read more here.
Keywords: microscopy; skin pigmentation; cutaneous hyperchromias; pigmentation confocal ... See more keywords
Melasma: How hormones can modulate skin pigmentation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.12877
Abstract: We described—along with a genetic predisposition and exposure to sunlight, as the main factors for melasma development—pregnancy, hormonal therapies, and oral contraceptive pills. Whilst hormonal alteration or therapies are frequently reported in literature in association… read more here.
Keywords: melasma hormones; dermatology; skin pigmentation; hormones modulate ... See more keywords
Seasonal Tanning-Induced Increases in Skin Pigmentation Do Not Affect Nitric Oxide-Mediated Vasodilation of the Cutaneous Microvasculature
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5730992
Abstract: Acute ultraviolet radiation (UVR) exposure reduces nitric oxide (NO)-dependent cutaneous vasodilation. Additionally, increased constitutive skin melanin concentrations are associated with reduced NO-dependent cutaneous vasodilation. However, the impact of seasonal tanning-induced increases in skin melanin concentration… read more here.
Keywords: skin pigmentation; vasodilation; local heating; physiology ... See more keywords