In vitro, Ex vivo and In vivo Approaches for Investigation of Skin Scarring: Human and Animal Models.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in wound care"
DOI: 10.1089/wound.2021.0139
Abstract: Significance The cutaneous repair process naturally results in different types of scarring that are classified as normal or pathological. Affected individuals are often affected from an aesthetic, physical (functional) and psychosocial perspective. The distinct nature… read more here.
Keywords: vitro vivo; vivo; skin scarring; animal models ... See more keywords
JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models
Sign Up to like & getrecommendations! Published in 2021 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abb3312
Abstract: Description JUN drives scarring by modifying the roles of fibroblast subpopulations, and JUN antagonism via CD36 may represent an antiscarring therapy. Scar wars Scars developing after skin wound can cause important functional, aesthetic, psychological, and… read more here.
Keywords: skin scarring; via cd36; jun; cd36 ... See more keywords
Alloplant biomaterials as postburn skin scarring inhibitors
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DOI: 10.17816/ov10222-28
Abstract: Allotransplants for eyelid frame plasty by “Alloplant”® may facilitate recovery of eyelid anatomical position and function and prevent postburn scar tissue traction. Purpose of the study. To determine the level of fibrogenic factors after skin… read more here.
Keywords: skin scarring; postburn skin; biomaterials postburn; tissue ... See more keywords
Skin scarring: Latest update on objective assessment and optimal management
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.942756
Abstract: Although skin scarring is considered by some to be a minor, unavoidable consequence in response to skin injury, for many patients, cosmetically unsightly scars may cause uncomfortable symptoms and loss of function plus significant psycho-social… read more here.
Keywords: optimal management; assessment; scar; management ... See more keywords
The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring
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DOI: 10.3390/pharmaceutics15041065
Abstract: Background Hypertrophic scars can cause pain, movement restrictions, and reduction of quality of life. Despite numerous options to tackle hypertrophic scarring, efficient therapies are still scarce, and cellular mechanisms are not well understood. Secreted factors… read more here.
Keywords: skin scarring; irradiated peripheral; mononuclear cells; pbmcsec ... See more keywords