Ribonucleoproteins Mediated Efficient In Vivo Gene Editing in Skin Stem Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/7651_2018_115
Abstract: The clustered regularly interspaced, short palindromic repeats (CRISPR)-Cas9 system functions like an adaptive immune system in a variety of microbes and has recently been engineered as a powerful tool for manipulating genomic sequences in a… read more here.
Keywords: skin stem; stem cells; vivo gene; gene editing ... See more keywords
Skin Stem Cells in Silence, Action, and Cancer
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2018.04.008
Abstract: In studying how stem cells make and maintain tissues, nearly every chapter of a cell biology textbook takes on special interest. The field even allows us to venture where no chapters have yet been written.… read more here.
Keywords: skin stem; cells silence; silence action; biology ... See more keywords
Extracellular serine feeds cancer skin stem cells
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/s41580-020-0261-9
Abstract: Premalignant skin stem cells become dependent on extracellular serine for proliferation, and this metabolic reprogramming inhibits tumour-suppressing cell differentiation. read more here.
Keywords: skin stem; stem cells; serine feeds; extracellular serine ... See more keywords
Immune privilege of skin stem cells: What do we know and what can we learn?
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Dermatology"
DOI: 10.1111/exd.14221
Abstract: The skin forms a barrier that prevents dehydration and keeps us safe from pathogens. To ensure proper function, the skin possesses a myriad of stem cell populations that are essential for maintenance and repair upon… read more here.
Keywords: skin stem; immune privilege; skin; stem ... See more keywords