Evaluation of a Comprehensive Skin Toxicity Program for Patients Treated With Epidermal Growth Factor Receptor Inhibitors at a Cancer Treatment Center.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2020.1795
Abstract: Importance Up to 90% of patients treated with an epidermal growth factor receptor inhibitor (EGFRi) experience cutaneous toxic effects that are negatively associated with quality of life and lead to treatment interruptions. The Skin Toxicity… read more here.
Keywords: skin toxicity; treatment; program; toxicity ... See more keywords
Compared with intensity‐modulated radiotherapy, image‐guided radiotherapy reduces severity of acute radiation‐induced skin toxicity during radiotherapy in patients with breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1630
Abstract: Radiotherapy (RT) is an effective treatment for breast cancer. The side effects of breast irradiation, including skin toxicity in the irradiation field, cause considerable discomfort. This study compared the severity of skin toxicity caused by… read more here.
Keywords: skin toxicity; radiotherapy; breast cancer; severity ... See more keywords
EVITA—a double-blind, vehicle-controlled, randomized phase II trial of vitamin K1 cream as prophylaxis for cetuximab-induced skin toxicity
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Oncology"
DOI: 10.1093/annonc/mdy015
Abstract: Background Acne-like skin rash is a frequently occurring adverse event associated with drugs against the epidermal growth factor receptor. This randomized vehicle-controlled study investigated the addition of vitamin K1 cream to doxycycline in patients with… read more here.
Keywords: skin toxicity; skin rash; skin; vitamin cream ... See more keywords
A protective effect of morning radiotherapy on acute skin toxicity in patients with breast cancer
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000027155
Abstract: Abstract The focus of this prospective cohort study was to evaluate the risk factors of severe acute skin toxicity (grade ≥2) in 100 patients with breast cancer (BC) during radiotherapy (RT). The patients were evaluated… read more here.
Keywords: toxicity; breast cancer; skin toxicity; acute skin ... See more keywords
Follicular T helper cells and cutaneous T‐cell lymphomas
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Dermatology"
DOI: 10.1111/bjd.21839
Abstract: centre retrospective international cohort study designed to investigate clinical associations of skin toxicities induced by different ICI therapies. The study revealed that ICI-induced cutaneous toxicities may depend on certain factors, such as the specific agent… read more here.
Keywords: cell; follicular helper; cutaneous toxicities; skin toxicities ... See more keywords
Abstract 1623: Response and skin toxicity related protein signature in late stage melanoma patients after anti-PD-1 treatment
Sign Up to like & getrecommendations! Published in 2021 at "Immunology"
DOI: 10.1158/1538-7445.am2021-1623
Abstract: Skin toxicity after anti-PD1 treatment in melanoma patients is the most common type of immune related adverse effect (irAE) and has been associated with improved overall response rate and survival. Nonetheless, not many mechanistic biomarkers… read more here.
Keywords: melanoma patients; response; toxicity; skin toxicity ... See more keywords
Efficacy of Prophylactic Traditional Chinese Medicine on Skin Toxicity of Afatinib in EGFR Mutation-Positive Advanced Lung Adenocarcinoma: A Single-Center, Prospective, Double-Blinded, Randomized-Controlled Pilot Trial
Sign Up to like & getrecommendations! Published in 2022 at "Integrative Cancer Therapies"
DOI: 10.1177/15347354221086663
Abstract: Objectives: To evaluate the efficacy of prophylactic traditional Chinese medicine (TCM) on skin toxicities in patients with advanced lung adenocarcinoma treated with first-line epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in a randomized-controlled trial… read more here.
Keywords: skin toxicity; medicine; lung adenocarcinoma; advanced lung ... See more keywords
A phase 2 clinical trial on trametinib and low-dose dabrafenib in advanced pretreated BRAFV600/NRASQ61R/K/L wild-type melanoma (TraMel-WT): Interim efficacy and safety results.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.9529
Abstract: 9529 Background: The mitogen-activated protein kinase (MAPK) pathway can be activated by alternative driver mutations in BRAFV600/ NRASQ61R/K/L wild-type (wt) melanoma. MEK-inhibitor monotherapy has activity in BRAFV600/ NRASQ61R/K/L wt melanoma, but is associated with considerate… read more here.
Keywords: melanoma; brafv600 nrasq61r; trial; skin toxicity ... See more keywords
Identification of immune-related mechanisms of cetuximab induced skin toxicity in colorectal cancer patients
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0276497
Abstract: Skin rash is a well-known predictive marker of the response to cetuximab (Cmab) in metastatic colorectal cancer (mCRC). However, the mechanism of skin rash development is not well understood. Following exposure to EGFR-targeted therapies, changes… read more here.
Keywords: skin toxicity; skin rash; cmab; cycle ... See more keywords
Severe cumulative skin toxicity during toripalimab combined with vemurafenib following toripalimab alone
Sign Up to like & getrecommendations! Published in 2023 at "Open Life Sciences"
DOI: 10.1515/biol-2022-0606
Abstract: Targeted therapy and PD - 1/L1 inhibitors are the main treat - ments for BRAF V600 - mutated melanomas [ 1,2 ] . Recently, PD - 1 inhibitors for melanoma with toripalimab have been developed… read more here.
Keywords: vemurafenib following; toripalimab combined; toripalimab; skin toxicity ... See more keywords
Evaluation of acute skin toxicity during radiotherapy for breast cancer in elderly patients
Sign Up to like & getrecommendations! Published in 2020 at "Translational cancer research"
DOI: 10.21037/tcr.2019.07.01
Abstract: Background: For women with early stage breast cancer, the hypofractionation is the standard of care, whereas for women in other situations the standard dose is still recommended. Although the hypofractionation studies included elderly patients (>70… read more here.
Keywords: skin toxicity; breast; treatment; elderly patients ... See more keywords