Abstract 1764: Accurate and reproducible detection of fusions and exon skipping events in NSCLC-derived samples using a comprehensive, targeted RNA-Seq system across multiple laboratories
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-1764
Abstract: • Targeted RNA-Seq of expression markers in NSCLC FFPE tumors requires integrated reagents, protocols, and interpretive software that can ensure consistent results across laboratories. • In this study, a comprehensive targeted NGS system, the QuantideX®… read more here.
Keywords: skipping events; system; targeted rna; comprehensive targeted ... See more keywords
Identification of exon skipping events associated with Alzheimer’s disease in the human hippocampus
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DOI: 10.1186/s12920-018-0453-8
Abstract: BackgroundAt least 90% of human genes are alternatively spliced. Alternative splicing has an important function regulating gene expression and miss-splicing can contribute to risk for human diseases, including Alzheimer’s disease (AD).MethodsWe developed a splicing decision… read more here.
Keywords: human hippocampus; skipping events; alzheimer disease; exon skipping ... See more keywords