Articles with "skov3" as a keyword



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Investigating function of long noncoding RNA of HOTAIRM1 in progression of SKOV3 ovarian cancer cells.

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Published in 2021 at "Drug development research"

DOI: 10.1002/ddr.21821

Abstract: Ovarian cancer is one of the most heterogeneous malignancies in the field of gynecologic oncology. Deregulation of long noncoding RNAs (lncRNAs) is implicated in carcinogenesis. Therefore, the present study was conducted to investigate the possible… read more here.

Keywords: hotairm1; ovarian cancer; skov3; hotairm1 progression ... See more keywords
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Ursolic acid reduces Adriamycin resistance of human ovarian cancer cells through promoting the HuR translocation from cytoplasm to nucleus

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Published in 2020 at "Environmental Toxicology"

DOI: 10.1002/tox.23032

Abstract: Ursolic acid (UA) has been shown to suppress various tumor progression, however, its roles in Adriamycin resistance of human ovarian cancer (OC) cells are still unclear. This work aims to investigate the effects of UA… read more here.

Keywords: skov3; ursolic acid; hur; resistance ... See more keywords
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Antitumor activity of triptolide in SKOV3 cells and SKOV3/DDP in vivo and in vitro

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Published in 2020 at "Anti-Cancer Drugs"

DOI: 10.1097/cad.0000000000000894

Abstract: This study was designed to investigate the antitumor activity of triptolide in ovarian cancer inoculated with SKOV3 and SKOV3/cisplatin (DDP) cells, and to assess the mechanisms. In-vivo and in-vitro experiments were designed to evaluate the… read more here.

Keywords: skov3 ddp; skov3; factor; group ... See more keywords
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Comparative glycoproteomics study on the surface of SKOV3 versus IOSE80 cell lines

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Published in 2022 at "Frontiers in Chemistry"

DOI: 10.3389/fchem.2022.1010642

Abstract: Objective: Site- and structure-specific quantitative N-glycoproteomics study of differential cell-surface N-glycosylation of ovarian cancer SKOV3 cells with the non-cancerous ovarian epithelial IOSE80 cells as the control. Methods: C18-RPLC-MS/MS (HCD with stepped normalized collision energies) was… read more here.

Keywords: cell; structure; surface; skov3 ... See more keywords

HOXB9 Overexpression Confers Chemoresistance to Ovarian Cancer Cells by Inducing ERCC-1, MRP-2, and XIAP

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24021249

Abstract: The purpose of this study was to identify the role of HOXB9 and associated molecular mechanism in acquiring chemoresistance to ovarian cancer cells. After establishing HOXB9-overexpressing cells (HOXB9-OE/SKOV3), cisplatin resistance-induced cells (Cis-R/SKOV3), and an ovarian… read more here.

Keywords: mrp xiap; mrp; skov3; hoxb9 ... See more keywords
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Silencing the expression of MTDH increases the radiation sensitivity of SKOV3 ovarian cancer cells and reduces their proliferation and metastasis.

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Published in 2018 at "International journal of oncology"

DOI: 10.3892/ijo.2018.4541

Abstract: Ovarian cancer has a high mortality rate among women worldwide. Radiotherapy is considered an effective method of ovarian cancer treatment, however, radioresistance presents a challenge. It is necessary to develop techniques that can increase radiosensitivity… read more here.

Keywords: skov3; proliferation; mtdh silencing; ovarian cancer ... See more keywords
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TPX2 silencing mediated by joint action of microvesicles and ultrasonic radiation inhibits the migration and invasion of SKOV3 cells

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Published in 2018 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2018.8810

Abstract: Ovarian cancer, with its high morbidity, has one of the highest mortality rates among gynecological malignant tumors. Overexpression of targeting protein for Xklp2 (TPX2) has been identified in numerous malignant tumors. The present study sought… read more here.

Keywords: skov3; microvesicles ultrasonic; tpx2; ultrasonic radiation ... See more keywords
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Artemisinin induced reversal of EMT affects the molecular biological activity of ovarian cancer SKOV3 cell lines

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Published in 2019 at "Oncology Letters"

DOI: 10.3892/ol.2019.10608

Abstract: Accumulating evidence suggests that celecoxib and artemisinin could mediate ovarian cancer development and metastasis. The present study investigated the effects of celecoxib and artemisinin on the epithelial-mesenchymal transition (EMT) characteristics of the human ovarian epithelial… read more here.

Keywords: emt; skov3; expression; ovarian cancer ... See more keywords