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   Articles with "skov3 ddp" as a keyword



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Antitumor activity of triptolide in SKOV3 cells and SKOV3/DDP in vivo and in vitro

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recommendations! Published in 2020 at "Anti-Cancer Drugs"

DOI: 10.1097/cad.0000000000000894

Abstract: This study was designed to investigate the antitumor activity of triptolide in ovarian cancer inoculated with SKOV3 and SKOV3/cisplatin (DDP) cells, and to assess the mechanisms. In-vivo and in-vitro experiments were designed to evaluate the… read more here.

Keywords: skov3 ddp; skov3; factor; group ... See more keywords
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ABT737 reverses cisplatin resistance by targeting glucose metabolism of human ovarian cancer cells

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recommendations! Published in 2018 at "International Journal of Oncology"

DOI: 10.3892/ijo.2018.4476

Abstract: The poor prognosis and high mortality of patients with ovarian cancer result in part from their poor response to platinum-based chemotherapy. However, the precise mechanism behind cisplatin resistance is still not fully understood. In the… read more here.

Keywords: metabolism; skov3 ddp; glucose metabolism; ovarian cancer ... See more keywords
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Glutathione S‑transferase isozyme alpha 1 is predominantly involved in the cisplatin resistance of common types of solid cancer.

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recommendations! Published in 2019 at "Oncology reports"

DOI: 10.3892/or.2018.6861

Abstract: The roles of glutathione S‑transferase pi 1 (GSTP1), glutathione S‑transferase mu 2 (GSTM2) and glutathione S‑transferase alpha 1 (GSTA1) in cisplatin (DDP)‑resistance of solid cancer cells (A549/DDP, SKOV3/DDP and SGC7901/DDP) were compared following expression downregulation… read more here.

Keywords: ddp; sgc7901 ddp; skov3 ddp; a549 ddp ... See more keywords
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p62 Suppressed VK3-induced Oxidative Damage Through Keap1/Nrf2 Pathway In Human Ovarian Cancer Cells

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recommendations! Published in 2020 at "Journal of Cancer"

DOI: 10.7150/jca.34423

Abstract: Imbalance of redox homeostasis may be responsible for the resistance of cancer to chemotherapy. Currently, increasing studies demonstrated that vitamin K3 (VK3), which promoted the production of ROS, had potential to be developed as an… read more here.

Keywords: oxidative damage; ddp cells; keap1; skov3 ddp ... See more keywords