SLAMF6 is associated with the susceptibility and severity of rheumatoid arthritis in the Chinese population
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DOI: 10.1186/s13018-021-02901-9
Abstract: Objectives A recently published genome-wide association study identified six novel loci associated with rheumatoid arthritis (RA) in Korean population. We aimed to investigate whether these newly reported RA-risk loci are associated with RA in the… read more here.
Keywords: expression; rheumatoid arthritis; patients controls; chinese population ... See more keywords
SLAMF6 compartmentalization enhances T cell functions
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DOI: 10.26508/lsa.202201533
Abstract: After stimulation, the T cell co-receptor SLAMF6 colocalizes with the TCR–CD3 complex to enhance T cell activation. Targeting SLAMF6 localization and function with bispecific antibodies is a novel mechanism with potential therapeutic translation. Signaling lymphocyte… read more here.
Keywords: cell; slamf6; cell activation; cell receptor ... See more keywords