SLAMF7-CAR T cells eliminate myeloma and confer selective fratricide of SLAMF7+ normal lymphocytes.
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DOI: 10.1182/blood-2017-04-778423
Abstract: SLAMF7 is under intense investigation as a target for immunotherapy in multiple myeloma. In this study, we redirected the specificity of T cells to SLAMF7 through expression of a chimeric antigen receptor (CAR) derived from… read more here.
Keywords: slamf7; myeloma; slamf7 car; normal lymphocytes ... See more keywords