SHARPIN promotes cell proliferation of cholangiocarcinoma and inhibits ferroptosis via p53/SLC7A11/GPX4 signaling
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DOI: 10.1111/cas.15531
Abstract: SHARPIN is a tumor‐associated gene involved in the growth and proliferation of many tumor types. A function of SHARPIN in cholangiocarcinoma (CCA) is so far unclear. Here, we studied the role and function of SHARPIN… read more here.
Keywords: cell proliferation; proliferation; slc7a11 gpx4; p53 ... See more keywords
Prognostic and Immunological Role of Key Genes of Ferroptosis in Pan-Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.748925
Abstract: Solute carrier family 7 member 11 (SLC7A11), glutathione peroxidase 4 (GPX4), and apoptosis inducing factor mitochondria associated 2 (AIFM2) are the key regulators in ferroptosis. However, the expression patterns and prognostic roles of these genes… read more here.
Keywords: pan cancer; slc7a11 gpx4; infiltration; expression ... See more keywords