The Role of Cystine/Glutamate Antiporter SLC7A11/xCT in the Pathophysiology of Cancer
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DOI: 10.3389/fonc.2022.858462
Abstract: SLC7A11/xCT is an antiporter that mediates the uptake of extracellular cystine in exchange for glutamate. Cystine is reduced to cysteine, which is a rate-limiting precursor in glutathione synthesis; a process that protects cells from oxidative… read more here.
Keywords: cancer; antiporter; slc7a11 xct; cystine ... See more keywords