Nature of T cell epitopes in lupus antigens and HLA-DR determines autoantibody initiation and diversification
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DOI: 10.1136/annrheumdis-2018-214125
Abstract: Objectives The generation of systemic lupus erythematosus (SLE)-related autoantibodies have been shown to be T cell dependent and antigen driven with HLA-DR restriction. In this study, the initiating antigen(s) and the mechanism of autoantibody diversification… read more here.
Keywords: autoantibody; cell epitopes; diversification; related autoantibodies ... See more keywords
Rare case of bilateral wrist and foot drop from SLE-related vasculitic polyneuropathy
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DOI: 10.1136/bcr-2019-232890
Abstract: Systemic lupus erythematosus (SLE) is a heterogeneous, chronic, inflammatory, autoimmune disease characterised by multiorgan involvement and the production of multiple autoantibodies. Neurological manifestations in SLE patients are frequently reported—the prevalence is 37%–90%. We present a… read more here.
Keywords: wrist foot; foot drop; bilateral wrist; related vasculitic ... See more keywords
Prevalence, involved domains, and predictor of cognitive dysfunction in systemic lupus erythematosus
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DOI: 10.1177/0961203320958061
Abstract: Background Cognitive Dysfunction (CD) can occur in Systemic Lupus Erythematosus (SLE) before the occurrence of Neuropsychiatric Lupus Erythematosus (NPSLE). Given the reversibility and fluctuation of SLE-related CD, the research for possible predictors is of great… read more here.
Keywords: sle; sle related; lupus erythematosus; prevalence ... See more keywords
Triglycerides as Biomarker for Predicting Systemic Lupus Erythematosus Related Kidney Injury of Negative Proteinuria
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DOI: 10.3390/biom12070945
Abstract: Fewer biomarkers can be used to predict systemic lupus erythematosus (SLE) related kidney injury. This paper presents an apriori algorithm of association rules to mine the predictive biomarkers for SLE-related kidney injury of negative proteinuria.… read more here.
Keywords: sle related; negative proteinuria; kidney injury; related kidney ... See more keywords