Marshalling the senses for a good night's sleep
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22553
Abstract: K LE B E R C O R D E IR O / S H U TT E R S TO C K .C O M R esearchers have long known that a poor night… read more here.
Keywords: cancer; sleep drive; night sleep; sleep ... See more keywords
Sleep drive is coupled to tissue damage via shedding of Caenorhabditis elegans EGFR ligand SISS-1
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-55252-4
Abstract: The benefits of sleep extend beyond the nervous system. Peripheral tissues impact sleep regulation, and increased sleep is observed in response to damaging conditions, even those that selectively affect non-neuronal cells. However, the ‘sleep need’… read more here.
Keywords: elegans egfr; stress; damage; sleep drive ... See more keywords
Sleep drive, not total sleep amount, increases seizure risk
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-62311-x
Abstract: Sleep loss has been associated with increased seizure risk since antiquity. Using automated video detection of spontaneous seizures in Drosophila epilepsy models, we show that seizures worsen only when sleep restriction raises homeostatic “sleep drive,”… read more here.
Keywords: sleep amount; seizure risk; seizure; sleep drive ... See more keywords
0044 Sleep Need-dependent Plasticity of a Thalamic Circuit Generates Persistence of Sleep Drive
Sign Up to like & getrecommendations! Published in 2024 at "SLEEP"
DOI: 10.1093/sleep/zsae067.0044
Abstract: Prolonged wakefulness leads to persistent, deep recovery sleep. However, the neuronal circuits mediating this process remain elusive. Here, starting from a large circuit screen, we identify and characterize a group of thalamic nucleus reuniens (RE)… read more here.
Keywords: recovery sleep; circuit; sleep drive; sleep need ... See more keywords