Cortical hierarchy underlying homeostatic sleep pressure alleviation
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-64989-5
Abstract: Sleep dissipates accumulated sleep pressure and restores brain function, yet how this recovery unfolds across the cortical hierarchy remains unclear. Here, we record simultaneous electroencephalogram (EEG) and blood oxygen level-dependent (BOLD) functional magnetic resonance imaging… read more here.
Keywords: pressure alleviation; cortical hierarchy; sleep pressure; hierarchy underlying ... See more keywords
Local sleep-like events during wakefulness and their relationship to decreased alertness in astronauts on ISS
Sign Up to like & getrecommendations! Published in 2019 at "NPJ Microgravity"
DOI: 10.1038/s41526-019-0069-0
Abstract: Adequate sleep quantity and quality is required to maintain vigilance, cognitive and learning processes. A decrease of sleep quantity preflight and on the International Space Station (ISS) has been reported. Recent counter-measures have been implemented… read more here.
Keywords: like events; space; local sleep; sleep pressure ... See more keywords
Sleep pressure modulates single-neuron synapse number in zebrafish
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DOI: 10.1038/s41586-024-07367-3
Abstract: Sleep is a nearly universal behaviour with unclear functions1. The synaptic homeostasis hypothesis proposes that sleep is required to renormalize the increases in synaptic number and strength that occur during wakefulness2. Some studies examining either… read more here.
Keywords: pressure; number; synapse; single neuron ... See more keywords
Covert sleep-related biological processes are revealed by probabilistic analysis in Drosophila
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1917573117
Abstract: Significance Reduced sleep duration and disrupted sleep quality are correlated with adverse mental and physical health outcomes. Better tools for measuring the internal drives for sleep and wake in model organisms would facilitate understanding the… read more here.
Keywords: analysis; sleep pressure; sleep; analysis drosophila ... See more keywords
0044 Sleep Need-dependent Plasticity of a Thalamic Circuit Generates Persistence of Sleep Drive
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DOI: 10.1093/sleep/zsae067.0044
Abstract: Prolonged wakefulness leads to persistent, deep recovery sleep. However, the neuronal circuits mediating this process remain elusive. Here, starting from a large circuit screen, we identify and characterize a group of thalamic nucleus reuniens (RE)… read more here.
Keywords: recovery sleep; circuit; sleep drive; sleep need ... See more keywords