Sleep Spindle Refractoriness Segregates Periods of Memory Reactivation
Sign Up to like & getrecommendations! Published in 2018 at "Current Biology"
DOI: 10.1016/j.cub.2018.04.020
Abstract: The stability of long-term memories is enhanced by reactivation during sleep. Correlative evidence has linked memory reactivation with thalamocortical sleep spindles, although their functional role is not fully understood. Our initial study replicated this correlation and… read more here.
Keywords: sleep spindle; reactivation; memory reactivation; memory ... See more keywords
Sleep spindle and slow wave abnormalities in schizophrenia and other psychotic disorders: Recent findings and future directions
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia Research"
DOI: 10.1016/j.schres.2019.11.002
Abstract: Sleep spindles and slow waves are the two main oscillatory activities occurring during NREM sleep. Slow waves are ∼1 Hz, high amplitude, negative-positive deflections that are primarily generated and coordinated within the cortex, whereas sleep spindles… read more here.
Keywords: sleep spindle; spindle slow; slow wave; psychotic disorders ... See more keywords
Infant sleep EEG features at 4 months as biomarkers of neurodevelopment at 18 months
Sign Up to like & getrecommendations! Published in 2025 at "Pediatric Research"
DOI: 10.1038/s41390-025-03893-6
Abstract: Sleep parameters evolve in parallel with neurodevelopment. Sleep participates in synaptic homeostasis and memory consolidation and infant sleep parameters correlate with later aspects of early childhood cognition. Typically developing, term-born infants had a diurnal sleep-EEG… read more here.
Keywords: duration; sleep spindle; biomarkers neurodevelopment; infant sleep ... See more keywords
Association between early stage N2 sleep spindle burst characteristics and vigilance groups: an observational study on patients from a tertiary sleep centre
Sign Up to like & getrecommendations! Published in 2022 at "Physiological Measurement"
DOI: 10.1088/1361-6579/ac77d2
Abstract: Objective. Obstructive sleep apnoea (OSA) is associated with impaired vigilance. This paper examines the hypothesis that sleep spindle (Sp) characteristics during nocturnal sleep can be mapped to vigilance deficits measured by the psychomotor vigilance task… read more here.
Keywords: burst characteristics; spindle burst; vigilance groups; cohort ... See more keywords
Inflammation, tau pathology, and synaptic integrity associated with sleep spindles and memory prior to β-amyloid positivity.
Sign Up to like & getrecommendations! Published in 2022 at "Sleep"
DOI: 10.1093/sleep/zsac135
Abstract: STUDY OBJECTIVES Fast frequency sleep spindles are reduced in aging and Alzheimer's disease (AD), but the mechanisms and functional relevance of these deficits remains unclear. The study objective was to identify AD biomarkers associated with… read more here.
Keywords: prior amyloid; positivity; pathology; sleep spindle ... See more keywords
Sleep Spindle Alterations Relate to Working Memory Deficits in Individuals at Clinical High Risk for Psychosis.
Sign Up to like & getrecommendations! Published in 2022 at "Sleep"
DOI: 10.1093/sleep/zsac193
Abstract: STUDY OBJECTIVES Sleep spindles are waxing and waning EEG waves exemplifying the main fast oscillatory activity occurring during NREM sleep. Several recent studies have established that sleep spindle abnormalities are present in schizophrenia spectrum disorders,… read more here.
Keywords: individuals clinical; high risk; risk; sleep spindle ... See more keywords
0533 Sleep Spindle Features in Obstructive Sleep Apnea: Results from the Sleep Heart Health Study
Sign Up to like & getrecommendations! Published in 2024 at "SLEEP"
DOI: 10.1093/sleep/zsae067.0533
Abstract: Obstructive sleep apnea (OSA) is associated with altered cognitive function and dementia, but the mechanisms underlying these associations remain unclear. One proposed mechanism is that OSA, by chronically fragmenting sleep, decreases the number and activity… read more here.
Keywords: sleep spindle; spindle density; sleep; apnea ... See more keywords
1240 Decreased Sleep Spindle Density Is Associated with Suicidality in Young Adults: The Penn State Child Cohort
Sign Up to like & getrecommendations! Published in 2025 at "SLEEP"
DOI: 10.1093/sleep/zsaf090.1240
Abstract: Sleep spindle deficits have been observed in different forms of psychopathology. Young adulthood is a developmental stage associated with increased rates of psychopathology and suicidality. Whether deficits in sleep spindle density (SSD) are associated with… read more here.
Keywords: sleep spindle; young adults; psychopathology; suicidality young ... See more keywords
Fast sleep spindle density is associated with rs4680 (Val108/158Met) genotype of catechol-O-methyltransferase (COMT)
Sign Up to like & getrecommendations! Published in 2018 at "SLEEP"
DOI: 10.1093/sleep/zsy007
Abstract: Study Objectives Sleep spindles are a hallmark of NREM stage 2 sleep. Fast sleep spindles correlate with cognitive functioning and are reduced in schizophrenia. Although spindles are highly genetically determined, distinct genetic mechanisms influencing sleep… read more here.
Keywords: sleep spindle; spindle density; comt; val108 158met ... See more keywords
OpenSpindleNet: An Open-Source Deep Learning Network for Reliable Sleep Spindle Detection
Sign Up to like & getrecommendations! Published in 2025 at "Computers in biology and medicine"
DOI: 10.1101/2025.04.13.25325696
Abstract: Sleep spindles, an oscillatory brain activity occurring during light non-rapid eye movement (NREM) sleep, are important for memory consolidation and cognitive functions. Accurate detection is important for understanding the role of spindles in sleep state… read more here.
Keywords: detection; open source; sleep spindle; sleep spindles ... See more keywords
Convolutional Multiple Instance Learning for Sleep Spindle Detection With Label Refinement
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Transactions on Cognitive and Developmental Systems"
DOI: 10.1109/tcds.2022.3159285
Abstract: Sleep spindles are closely associated with cognitive functions and neurological disorders; thus, spindle detection has been an important topic in sleep medicine. Recently, machine learning approaches have shown the potential in automatic sleep spindle detection… read more here.
Keywords: spindle detection; feature learning; label refinement; sleep spindle ... See more keywords