Sleep Spindle Refractoriness Segregates Periods of Memory Reactivation
Sign Up to like & getrecommendations! Published in 2018 at "Current Biology"
DOI: 10.1016/j.cub.2018.04.020
Abstract: The stability of long-term memories is enhanced by reactivation during sleep. Correlative evidence has linked memory reactivation with thalamocortical sleep spindles, although their functional role is not fully understood. Our initial study replicated this correlation and… read more here.
Keywords: sleep spindle; reactivation; memory reactivation; memory ... See more keywords
Sleep spindle and slow wave abnormalities in schizophrenia and other psychotic disorders: Recent findings and future directions
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia Research"
DOI: 10.1016/j.schres.2019.11.002
Abstract: Sleep spindles and slow waves are the two main oscillatory activities occurring during NREM sleep. Slow waves are ∼1 Hz, high amplitude, negative-positive deflections that are primarily generated and coordinated within the cortex, whereas sleep spindles… read more here.
Keywords: sleep spindle; spindle slow; slow wave; psychotic disorders ... See more keywords
Association between early stage N2 sleep spindle burst characteristics and vigilance groups: an observational study on patients from a tertiary sleep centre
Sign Up to like & getrecommendations! Published in 2022 at "Physiological Measurement"
DOI: 10.1088/1361-6579/ac77d2
Abstract: Objective. Obstructive sleep apnoea (OSA) is associated with impaired vigilance. This paper examines the hypothesis that sleep spindle (Sp) characteristics during nocturnal sleep can be mapped to vigilance deficits measured by the psychomotor vigilance task… read more here.
Keywords: burst characteristics; spindle burst; vigilance groups; cohort ... See more keywords
Inflammation, tau pathology, and synaptic integrity associated with sleep spindles and memory prior to β-amyloid positivity.
Sign Up to like & getrecommendations! Published in 2022 at "Sleep"
DOI: 10.1093/sleep/zsac135
Abstract: STUDY OBJECTIVES Fast frequency sleep spindles are reduced in aging and Alzheimer's disease (AD), but the mechanisms and functional relevance of these deficits remains unclear. The study objective was to identify AD biomarkers associated with… read more here.
Keywords: prior amyloid; positivity; pathology; sleep spindle ... See more keywords
Sleep Spindle Alterations Relate to Working Memory Deficits in Individuals at Clinical High Risk for Psychosis.
Sign Up to like & getrecommendations! Published in 2022 at "Sleep"
DOI: 10.1093/sleep/zsac193
Abstract: STUDY OBJECTIVES Sleep spindles are waxing and waning EEG waves exemplifying the main fast oscillatory activity occurring during NREM sleep. Several recent studies have established that sleep spindle abnormalities are present in schizophrenia spectrum disorders,… read more here.
Keywords: individuals clinical; high risk; risk; sleep spindle ... See more keywords
Fast sleep spindle density is associated with rs4680 (Val108/158Met) genotype of catechol-O-methyltransferase (COMT)
Sign Up to like & getrecommendations! Published in 2018 at "SLEEP"
DOI: 10.1093/sleep/zsy007
Abstract: Study Objectives Sleep spindles are a hallmark of NREM stage 2 sleep. Fast sleep spindles correlate with cognitive functioning and are reduced in schizophrenia. Although spindles are highly genetically determined, distinct genetic mechanisms influencing sleep… read more here.
Keywords: sleep spindle; spindle density; comt; val108 158met ... See more keywords
Convolutional Multiple Instance Learning for Sleep Spindle Detection With Label Refinement
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Transactions on Cognitive and Developmental Systems"
DOI: 10.1109/tcds.2022.3159285
Abstract: Sleep spindles are closely associated with cognitive functions and neurological disorders; thus, spindle detection has been an important topic in sleep medicine. Recently, machine learning approaches have shown the potential in automatic sleep spindle detection… read more here.
Keywords: spindle detection; feature learning; label refinement; sleep spindle ... See more keywords
Reliability of sleep spindle measurements in adolescents: How many nights are necessary?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Sleep Research"
DOI: 10.1111/jsr.12698
Abstract: Evidence of night‐to‐night variation in adolescent sleep spindle characteristics is lacking. Twelve adolescents (M = 15.8 ± 0.8 years, eight males) participated in a laboratory study involving 9 nights with 10 hr sleep opportunity. Sleep… read more here.
Keywords: sleep spindle; reliability sleep; measurements adolescents; spindle ... See more keywords
Sleep spindles as a diagnostic and therapeutic target for chronic pain
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Pain"
DOI: 10.1177/1744806920902350
Abstract: Pain is known to disrupt sleep patterns, and disturbances in sleep can further worsen pain symptoms. Sleep spindles occur during slow wave sleep and have established effects on sensory and affective processing in mammals. A… read more here.
Keywords: sleep spindle; pain sleep; target; sleep spindles ... See more keywords
Thalamocortical and intracortical laminar connectivity determines sleep spindle properties
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1006171
Abstract: Sleep spindles are brief oscillatory events during non-rapid eye movement (NREM) sleep. Spindle density and synchronization properties are different in MEG versus EEG recordings in humans and also vary with learning performance, suggesting spindle involvement… read more here.
Keywords: sleep spindle; system; connectivity; spindle properties ... See more keywords
Local and Transient Changes of Sleep Spindle Density During Series of Prefrontal Repetitive Transcranial Magnetic Stimulation in Patients With a Major Depressive Episode
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Human Neuroscience"
DOI: 10.3389/fnhum.2021.738605
Abstract: The neuromodulatory effects of brain stimulation therapies notably involving repetitive transcranial magnetic stimulation (rTMS) on nocturnal sleep, which is critically disturbed in major depression and other neuropsychiatric disorders, remain largely undetermined. We have previously reported… read more here.
Keywords: sleep spindle; post; rtms sessions; spindle density ... See more keywords