0750 Nocturnal Sleep Stability and Cerebrospinal Fluid Orexin-A Levels: Sleep and Wake Bouts
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DOI: 10.1093/sleep/zsaa056.746
Abstract: The orexin (ORX)/hypocretin system stabilizes sleep-wake regulation by sustaining long periods of wakefulness in humans and animals. We aimed to evaluate the relationships between cerebrospinal fluid (CSF) ORX levels and markers of nocturnal sleep stability… read more here.
Keywords: sleep wake; orx levels; orx; nocturnal sleep ... See more keywords
API: an Alternative View for Sleep Stability Analysis based on Automatic Detection of the A-Phases from the Cyclic Alternating Pattern.
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DOI: 10.1093/sleep/zsac217
Abstract: STUDY OBJECTIVES Sleep stability can be studied by evaluating the Cyclic Alternating Pattern (CAP) in electroencephalogram signals. The present study presents a novel approach for assessing sleep stability, developing an index based on the CAP… read more here.
Keywords: sleep stability; cap; alternating pattern; phase ... See more keywords
Association of CSF orexin-A levels and nocturnal sleep stability in patients with hypersomnolence
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DOI: 10.1212/wnl.0000000000010743
Abstract: Objective To evaluate the associations between CSF orexin-A (ORX) levels and markers of nocturnal sleep stability, assessed by polysomnography. Methods Nocturnal polysomnography data and ORX levels of 300 drug-free participants (55% men, 29.9±15.5 years, ORX… read more here.
Keywords: sleep stability; wake bouts; orx levels; nocturnal sleep ... See more keywords