Causal associations between sleep traits and four cardiac diseases: a Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14016
Abstract: Previous studies investigated the associations between sleep traits and cardiac diseases, but the evidence for the causal inferences was unclear. This study aimed to explore the causal relationship between sleep and cardiac diseases by virtue… read more here.
Keywords: cardiac diseases; mendelian randomization; causal; study ... See more keywords
Association of Sleep Traits and Heel Bone Mineral Density: Observational and Mendelian Randomization Studies
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4406
Abstract: Observational studies have suggested that sleep and circadian disturbances are potentially modifiable risk factors for low bone mineral density (BMD), but the causal relationship is unclear. This study aimed to (i) replicate the findings by… read more here.
Keywords: bone mineral; low ebmd; mendelian randomization; sleep traits ... See more keywords
Sleep traits and associated factors among people living with HIV/AIDS in Iran: a two-step clustering analysis
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DOI: 10.1038/s41598-024-53140-x
Abstract: Sleep plays an essential role in improving the quality of life of people living with HIV (PLWH); however, sleep traits in this population are not well studied. This study aims to evaluate the sleep traits… read more here.
Keywords: quality; insomnia; cluster; sleep quality ... See more keywords
Causal Association of Sleep Traits with All-Cause and Cause-Specific Mortality: A Prospective Cohort and Mendelian Randomization Study
Sign Up to like & getrecommendations! Published in 2025 at "Rejuvenation Research"
DOI: 10.1089/rej.2024.0058
Abstract: The study aimed to explore the association between different sleep traits and all-cause mortality as well as to validate causality in the association through mendelian randomization (MR). We analyzed 451,420 European ancestry participants from the… read more here.
Keywords: traits cause; mortality; causal; association ... See more keywords
Is disrupted sleep a risk factor for Alzheimer’s disease? Evidence from a two-sample Mendelian randomization analysis
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Epidemiology"
DOI: 10.1093/ije/dyaa183
Abstract: Abstract Background It is established that Alzheimer’s disease (AD) patients experience sleep disruption. However, it remains unknown whether disruption in the quantity, quality or timing of sleep is a risk factor for the onset of… read more here.
Keywords: risk; alzheimer disease; sleep traits; evidence ... See more keywords
454Relationships between sleep traits and metabolic profiles: evidence from multivariable regression and Mendelian randomization analyses
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Epidemiology"
DOI: 10.1093/ije/dyab168.236
Abstract: Sleep traits are associated with cardiometabolic disease. The aim of this study was to explore the causal effect of sleep traits (duration and insomnia) on multiple metabolic traits. We used age, sex and BMI adjusted… read more here.
Keywords: insomnia; mendelian randomization; sleep traits; duration ... See more keywords
Relationships of sleep traits with lung cancer risk: a prospective cohort study in UK Biobank.
Sign Up to like & getrecommendations! Published in 2021 at "Sleep"
DOI: 10.1093/sleep/zsab089
Abstract: STUDY OBJECTIVES To prospectively investigate the association between sleep traits and lung cancer risk, accounting for the interactions with genetic predisposition of lung cancer. METHODS We included 469,691 individuals free of lung cancer at recruitment… read more here.
Keywords: risk; sleep traits; cancer risk; lung cancer ... See more keywords
0060 Exploring the Bidirectional Causal Associations Between Sleep Traits and Metabolomic Profile in Humans
Sign Up to like & getrecommendations! Published in 2025 at "SLEEP"
DOI: 10.1093/sleep/zsaf090.0060
Abstract: Unhealthy sleep patterns are common phenomena which may lead to a spectrum of adverse cardiometabolic outcomes. Metabolites play pivotal roles in the relevant underlying mechanisms, yet the causal associations between sleep and metabolome in humans… read more here.
Keywords: sleep duration; associations sleep; causal associations; sensitivity ... See more keywords
The Relationship Between Sleep Traits and Tinnitus in UK Biobank: A Population-Based Cohort Study
Sign Up to like & getrecommendations! Published in 2022 at "Ear and Hearing"
DOI: 10.1097/aud.0000000000001273
Abstract: Objectives: Understanding the association between sleep traits and tinnitus could help prevent and provide appropriate interventions against tinnitus. Therefore, this study aimed to assess the relationship between different sleep patterns and tinnitus. Design: A cross-sectional… read more here.
Keywords: traits tinnitus; tinnitus; analysis; upsetting tinnitus ... See more keywords
Association of sleep traits with risk of hypertensive disorders of pregnancy: a mendelian randomization study
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DOI: 10.1097/hjh.0000000000003771
Abstract: Background: Unhealthy sleep patterns are common during pregnancy and have been associated with an increased risk of developing hypertensive disorders of pregnancy (HDPs) in observational studies. However, the causality underlying these associations remains uncertain. This… read more here.
Keywords: risk hdps; hypertensive disorders; risk; association ... See more keywords
No evidence linking sleep traits with white blood cell counts: Multivariable‐adjusted and Mendelian randomization analyses
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Clinical Investigation"
DOI: 10.1111/eci.14189
Abstract: Disturbances in habitual sleep have been associated with multiple age‐associated diseases. However, the biological mechanisms underpinning these associations remain largely unclear. We assessed the possible involvement of the circulating immune system by determining the associations… read more here.
Keywords: multivariable adjusted; traits white; cell counts; blood cell ... See more keywords