Slingshot homolog-1 amplifies mitochondrial abnormalities by distinctly impairing health and clearance of mitochondria.
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DOI: 10.1093/hmg/ddad006
Abstract: Accumulating toxic protein assemblies, including Aβ and tau, and dysfunctional mitochondria are associated with synaptic and neuronal loss in Alzheimer's disease (ad). Such accumulations are thought to be due to clearance defects in the autophagy-lysosome… read more here.
Keywords: clearance; health; terminal region; slingshot homolog ... See more keywords