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   Articles with "sln" as a keyword



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Retrospective validation of the laparoscopic ICG SLN mapping in patients with grade 3 endometrial cancer

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recommendations! Published in 2018 at "Journal of Cancer Research and Clinical Oncology"

DOI: 10.1007/s00432-018-2648-y

Abstract: PurposeTo evaluate the sensitivity, negative predictive value (NPV) and false-negative (FN) rate of the near infrared (NIR) indocyanine green (ICG) sentinel lymph node (SLN) mapping in patients with poorly differentiated endometrial cancer who have undergone… read more here.

Keywords: sln mapping; endometrial cancer; sln; icg ... See more keywords
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Nanoformulations for dimethyl fumarate: Physicochemical characterization and in vitro/in vivo behavior

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recommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"

DOI: 10.1016/j.ejpb.2017.04.011

Abstract: &NA; Dimethyl fumarate has been demonstrated useful in relapsing remitting multiple sclerosis treatment (Tecfidera®). Nevertheless, since Tecfidera® capsules induce flushing, gastro‐intestinal events and other more serious drawbacks, in this investigation a nanoparticle based system to… read more here.

Keywords: vivo; sln; vitro; characterization ... See more keywords
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Temperature-sensitive gel-loaded composite nanomedicines for the treatment of cervical cancer by vaginal delivery.

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recommendations! Published in 2020 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2020.119616

Abstract: In this study, toad venom (TV) and realgar were loaded into a poloxamer 188/407 (F127/F188)-based temperature-sensitive in situ gel (TISG) and encapsulated in solid lipid nanoparticles (TV-SLN) or ground nano-realgar (NR) to improve drug release… read more here.

Keywords: vaginal delivery; temperature sensitive; sln; gel ... See more keywords
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Does Delay to Operation Impact Sentinel Lymph Node Status among Patients with Melanoma?

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recommendations! Published in 2021 at "Journal of the American College of Surgeons"

DOI: 10.1016/j.jamcollsurg.2021.07.486

Abstract: Introduction: After melanoma diagnosis, various factors can delay therapy, including the COVID-19 pandemic. In this study, we examine the significance of surgical delay on sentinel lymph node (SLN) status in melanoma patients. Methods: Using the… read more here.

Keywords: surgical delay; delay; sln; sentinel lymph ... See more keywords
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Improvement of memory deficits in the rat model of Alzheimer's disease by erythropoietin-loaded solid lipid nanoparticles

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recommendations! Published in 2019 at "Neurobiology of Learning and Memory"

DOI: 10.1016/j.nlm.2019.107082

Abstract: Erythropoietin (EPO), a hematopoietic factor, is one of the promising neuroprotective candidates in neurodegenerative disorders such as Alzheimer's disease (AD). Due to the high molecular weight, hydrophilicity and rapid clearance from circulation, EPO could not… read more here.

Keywords: alzheimer disease; epo; sln; loaded solid ... See more keywords
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Prospective clinical trial of robotic sentinel lymph node assessment with isosulfane blue (ISB) and indocyanine green (ICG) in endometrial cancer and the impact of ultrastaging (NCT01818739).

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recommendations! Published in 2019 at "Gynecologic oncology"

DOI: 10.1016/j.ygyno.2019.03.252

Abstract: OBJECTIVES To assess the performance sentinel lymph node (SLN) biopsy and effect of ultrastaging in clinically early stage endometrial cancer. METHODS Patients with endometrial cancer prospectively enrolled after informed consent was obtained. The cervix was… read more here.

Keywords: endometrial cancer; sln; sentinel lymph; cancer ... See more keywords
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Conserved luminal C-terminal domain dynamically controls interdomain communication in sarcolipin.

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recommendations! Published in 2020 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.0c00418

Abstract: Sarcolipin (SLN) mediates Ca2+ transport and metabolism in muscle by regulating the activity of the Ca2+ pump SERCA. SLN has a conserved luminal C-terminal domain that contributes to the its functional divergence among homologous SERCA… read more here.

Keywords: luminal terminal; communication; conserved luminal; sln ... See more keywords
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Filgrastim loading in PLGA and SLN nanoparticulate system: a bioinformatics approach

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recommendations! Published in 2020 at "Drug Development and Industrial Pharmacy"

DOI: 10.1080/03639045.2020.1788071

Abstract: Abstract Objective In this research work, we hypothesized to predict the nanoparticulate system, best suited for targeted delivery of filgrastim. Significance: Targeted delivery of filgrastim to bone marrow is required to decrease the incidence of… read more here.

Keywords: filgrastim; system; sln; nanoparticulate system ... See more keywords
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Effectual nanotherapy against oral squamous cell carcinoma

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recommendations! Published in 2021 at "Drug Development and Industrial Pharmacy"

DOI: 10.1080/03639045.2021.1934858

Abstract: Abstract Objective Oral squamous cell carcinoma (OSCC) is a frequently occurring type of cancer leading loss of huge number of lives. Folic acid (FA) conjugated solid lipid nanoparticle (SLN) loaded paclitaxel (PTX) and ascorbic acid… read more here.

Keywords: cell carcinoma; oral squamous; squamous cell; sln ... See more keywords
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Formulation of the novel structure curcumin derivative–loaded solid lipid nanoparticles: synthesis, optimization, characterization and anti-tumor activity screening in vitro

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recommendations! Published in 2022 at "Drug Delivery"

DOI: 10.1080/10717544.2022.2092235

Abstract: Abstract This study investigated the effect of structural modification of Curcumin (CU) combined with the solid lipid nanoparticles (SLN) drug delivery system on anti-tumor activity in vitro. A new structure of Curcumin derivative (CU1) was… read more here.

Keywords: solid lipid; curcumin; sln; cu1 ... See more keywords
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Optimization of nimesulide-loaded solid lipid nanoparticles (SLN) by factorial design, release profile and cytotoxicity in human Colon adenocarcinoma cell line

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recommendations! Published in 2019 at "Pharmaceutical Development and Technology"

DOI: 10.1080/10837450.2018.1549075

Abstract: Abstract The aim of this work is development of a nontoxic, long-term stable solid lipid nanoparticles (SLN) formulation for the loading of Nimesulide (NiM) by a 22 factorial design. The optimized formulation was composed of… read more here.

Keywords: factorial design; sln; lipid nanoparticles; nim sln ... See more keywords