LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "slns" as a keyword



Photo from wikipedia

Sentinel Lymph Node Characterization with a Dual-Targeted Molecular Ultrasound Contrast Agent

Sign Up to like & get
recommendations! Published in 2017 at "Molecular Imaging and Biology"

DOI: 10.1007/s11307-017-1109-3

Abstract: PurposeThe purpose of this study was to assess the performance of molecular ultrasound with dual-targeted microbubbles to detect metastatic disease in the sentinel lymph nodes (SLNs) in swine model of naturally occurring melanoma. The SLN… read more here.

Keywords: contrast agent; dual targeted; slns; molecular ultrasound ... See more keywords
Photo by kellysikkema from unsplash

Simvastatin-Loaded PEGylated Solid Lipid Nanoparticles: Lipid Functionalization to Improve Blood Circulation

Sign Up to like & get
recommendations! Published in 2020 at "BioNanoScience"

DOI: 10.1007/s12668-020-00770-w

Abstract: The aim of the present work was to formulate simvastatin-loaded PEGylated solid lipid nanoparticles (PEG-SLNs) for prolonging blood circulation. Plain solid lipid nanoparticles (P-SLNs) were prepared by ethanol injection method. Prepared P-SLNs were PEGylated using… read more here.

Keywords: peg slns; simvastatin; slns; lipid nanoparticles ... See more keywords
Photo by hakannural from unsplash

Cervical injection for sentinel lymph nodes detection in endometrial cancers is controversial

Sign Up to like & get
recommendations! Published in 2018 at "Clinical and Translational Imaging"

DOI: 10.1007/s40336-018-0279-6

Abstract: We read the review article conducted by Crivellaro et al. and published online on 6 March 2018, to update the recent published literature on sentinel lymph node (SLN) procedures in endometrial cancer (ECs) [1]. Crivellaro… read more here.

Keywords: slns; ecs; injection; cervical injection ... See more keywords
Photo from wikipedia

Potential enhancement of metformin hydrochloride in solidified reverse micellar solution-based PEGylated lipid nanoparticles targeting therapeutic efficacy in diabetes treatment

Sign Up to like & get
recommendations! Published in 2022 at "Heliyon"

DOI: 10.1016/j.heliyon.2022.e09099

Abstract: Metformin hydrochloride (MH) is a widely used oral biguanide antihyperglycemic (antidiabetic) drug with poor bioavailability which necessitates the development of novel drug delivery systems such as PEGylated solid lipid nanoparticles for improving its therapeutic activity.… read more here.

Keywords: pegylated lipid; lipid nanoparticles; drug; spectroscopy ... See more keywords
Photo from wikipedia

PEGylated Solid Lipid Nanoparticles for Brain Delivery of Lipophilic Kiteplatin Pt(IV) Prodrugs: an In Vitro Study.

Sign Up to like & get
recommendations! Published in 2020 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2020.119351

Abstract: Here, polyethylene glycol (PEG)-stabilized solid lipid nanoparticles (SLNs) containing Pt(IV) prodrugs derived from kiteplatin were designed and proposed as novel nanoformulations potentially useful for the treatment of glioblastoma multiforme. Four different Pt(IV) prodrugs were synthesized,… read more here.

Keywords: vitro study; slns; lipid nanoparticles; brain ... See more keywords
Photo by profwicks from unsplash

Thymoquinone loaded chitosan - Solid lipid nanoparticles: Formulation optimization to oral bioavailability study

Sign Up to like & get
recommendations! Published in 2021 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2021.102565

Abstract: Abstract High lipophilicity, low bioavailability, and hostile gastrointestinal (GI) environment is the major concern in oral administration of thymoquinone (TQ). Herein, we developed chitosan (CS) modified solid lipid nanoparticles (SLNs) to improve oral bioavailability. SLNs… read more here.

Keywords: bioavailability; lipid nanoparticles; thymoquinone; oral bioavailability ... See more keywords
Photo by oraly from unsplash

Slowing down lipolysis significantly enhances the oral absorption of intact solid lipid nanoparticles.

Sign Up to like & get
recommendations! Published in 2019 at "Biomaterials science"

DOI: 10.1039/c9bm00873j

Abstract: Only a limited amount of orally administered lipid nanoparticles are absorbed as intact particles due to lipolysis by lipases in the gastrointestinal tract. It is hypothesized that by counteracting lipolysis, more particles will survive gastrointestinal… read more here.

Keywords: absorption intact; oral absorption; slns; lipolysis ... See more keywords
Photo by finnnyc from unsplash

Preparation and evaluation of inhalable dry powder containing glucosamine-conjugated gefitinib SLNs for lung cancer therapy

Sign Up to like & get
recommendations! Published in 2020 at "Drug Development and Industrial Pharmacy"

DOI: 10.1080/03639045.2020.1788063

Abstract: Abstract Gefitinib as an epidermal growth factor receptor tyrosine kinase inhibitor has strong potential in lung cancer therapy. However, a major challenge of using gefitinib is its toxicities. In the present study, we developed a… read more here.

Keywords: gefitinib; cancer therapy; slns; lung cancer ... See more keywords
Photo by sharonmccutcheon from unsplash

Solid lipid nanoparticles to improve bioaccessibility and permeability of orally administered maslinic acid

Sign Up to like & get
recommendations! Published in 2022 at "Drug Delivery"

DOI: 10.1080/10717544.2022.2086937

Abstract: Abstract Maslinic acid (MA) is a plant-derived, low water-soluble compound with antitumor activity. We have formulated MA in the form of solid lipid nanoparticles (SLNs) with three different shell compositions: Poloxamer 407 (PMA), dicarboxylic acid-Poloxamer… read more here.

Keywords: slns; solid lipid; maslinic acid; bioaccessibility ... See more keywords
Photo by fachrizalm from unsplash

Improved uptake and bioavailability of cinnamaldehyde via solid lipid nanoparticles for oral delivery

Sign Up to like & get
recommendations! Published in 2022 at "Pharmaceutical Development and Technology"

DOI: 10.1080/10837450.2022.2147542

Abstract: Abstract Objective The purpose of this experiment was to explore the effect of Solid lipid nanoparticles (SLNs) on improving the oral absorption and bioavailability of cinnamaldehyde (CA). Methods CA-SLNs were prepared by high-pressure homogenization and… read more here.

Keywords: slns; bioavailability cinnamaldehyde; solid lipid; bioavailability ... See more keywords
Photo by socalcaral from unsplash

The impact of sentinel lymph node mapping with hybrid single photon emission computed tomography/computed tomography in patients with melanoma. Comparison to planar radioisotopic lymphoscintigraphy

Sign Up to like & get
recommendations! Published in 2023 at "Melanoma Research"

DOI: 10.1097/cmr.0000000000000893

Abstract: We studied the diagnostic value of 16 slices of single photon emission computed tomography (SPECT)/computed tomography (CT) in the anatomical localization, image interpretation and extra-sentinel lymph nodes (SLNs) detection compared to dynamic and static planar… read more here.

Keywords: slns; computed tomography; spect; patients melanoma ... See more keywords