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Clozapine-Induced Gastrointestinal Hypomotility: A 22-Year Bi-National Pharmacovigilance Study of Serious or Fatal ‘Slow Gut’ Reactions, and Comparison with International Drug Safety Advice

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Published in 2017 at "CNS Drugs"

DOI: 10.1007/s40263-017-0448-6

Abstract: IntroductionClozapine is the preferred antipsychotic for treatment-resistant schizophrenia, but has significant adverse effects, including gastrointestinal hypomotility or ‘slow gut’, which may result in severe constipation, ileus, bowel obstruction, and even death. These gastrointestinal effects remain… read more here.

Keywords: clozapine; clozapine induced; slow gut; study ... See more keywords