Increased PINK1/Parkin-mediated mitophagy explains the improved brain protective effects of slow rewarming following hypothermia after cardiac arrest in rats
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DOI: 10.1016/j.expneurol.2020.113326
Abstract: Cerebral ischemia-reperfusion (I/R) after cardiac arrest (CA) induces mitochondrial dysfunction, and the timely removal of damaged mitochondria by mitophagy is reported to protect against cerebral I/R injury. Therapeutic hypothermia (TH) has become an important component… read more here.
Keywords: hypothermia; slow rewarming; rewarming group; pink1 parkin ... See more keywords