EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-45567-4
Abstract: A low quadriceps slow-twitch (ST), oxidative (relative to fast-twitch) fiber proportion is prevalent in chronic diseases such Chronic Obstructive Pulmonary Disease (COPD) and is associated with exercise limitation and poor outcomes. Benefits of an increased… read more here.
Keywords: muscle; slow twitch; twitch oxidative; muscle phenotype ... See more keywords
Anabolism, catabolism and proteomic analysis in the slow‐twitch muscle of pacu ( Piaractus mesopotamicus ) submitted to prolonged fasting followed by refeeding
Sign Up to like & getrecommendations! Published in 2019 at "Aquaculture Research"
DOI: 10.1111/are.14456
Abstract: Here, we aimed to study the slow muscle of the fish Piaractus mesopotamicus submitted to 30 days of fasting (D30) followed by 1 day (D31) or 30 days of refeeding (D60). Histological analysis of fibre diameter was performed… read more here.
Keywords: piaractus mesopotamicus; muscle; analysis; slow twitch ... See more keywords
Distinct effects of cell-free hemoglobin on oxygen pressure dynamics of fast vs. slow twitch muscle
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733233
Abstract: Hemolysis occurs following exposure to environmental stressors (e.g., microgravity) and in hemolytic diseases (e.g., sickle cell disease). When released from the red blood cell, cell-free hemoglobin (Hb) reduces nitric oxide (NO) availability and impacts skeletal… read more here.
Keywords: twitch muscle; cell free; muscle; slow twitch ... See more keywords
Distinct signal transductions in fast‐ and slow‐ twitch muscles upon denervation
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DOI: 10.14814/phy2.13606
Abstract: Denervation induces skeletal muscle atrophy, which primarily impairs oxidative slow twitch fibers. The underlying mechanism of this phenomenon, however, remains to be addressed. We hypothesize that denervation‐induced fiber‐specific atrophy may result from the distinct activities… read more here.
Keywords: upon denervation; slow twitch; denervation; edl ... See more keywords
Effect of Porcine Whole Blood Protein Hydrolysate on Slow-Twitch Muscle Fiber Expression and Mitochondrial Biogenesis via the AMPK/SIRT1 Pathway
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DOI: 10.3390/ijms23031229
Abstract: Skeletal muscle is a heterogeneous tissue composed of a variety of functionally different fiber types. Slow-twitch type I muscle fibers are rich with mitochondria, and mitochondrial biogenesis promotes a shift towards more slow fibers. Leucine,… read more here.
Keywords: twitch muscle; fiber; muscle; slow twitch ... See more keywords
Apocynin Attenuates Diabetes-Induced Skeletal Muscle Dysfunction by Mitigating ROS Generation and Boosting Antioxidant Defenses in Fast-Twitch and Slow-Twitch Muscles
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12050674
Abstract: In response to diabetes mellitus, skeletal muscle is negatively affected, as is evident by reduced contractile force production, increased muscle fatigability, and increased levels of oxidative stress biomarkers. Apocynin is a widely used NADPH oxidase… read more here.
Keywords: twitch; muscle; slow twitch; twitch slow ... See more keywords