Endogenous secretory leukocyte protease inhibitor inhibits microbial‐induced monocyte activation
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202249964
Abstract: In the intestine, epithelial factors condition incoming immune cells including monocytes to adapt their threshold of activation and prevent undesired inflammation. Colonic epithelial cells express Secretory Leukocyte Protease Inhibitor (SLPI), an inhibitor of NF kappa… read more here.
Keywords: slpi; monocyte activation; inhibitor; leukocyte protease ... See more keywords
Secretory leukocyte protease inhibitor regulates human periodontal ligament cell production of pro-inflammatory cytokines
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DOI: 10.1007/s00011-017-1062-2
Abstract: ObjectiveRegulation of immune-like cell properties of periodontal ligament (PDL) cells is not understood. We investigate the importance of secretory leukocyte protease inhibitor (SLPI) for production of pro-inflammatory cytokines in human PDL cells.Materials and methodsPDL cells… read more here.
Keywords: periodontal ligament; slpi; expression; cell ... See more keywords
Neonatal and maternal upregulation of antileukoproteinase in horses
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1395030
Abstract: Introduction The end of gestation, ensuing parturition, and the neonatal period represent highly dynamic phases for immunological changes in both mother and offspring. The regulation of innate immune cells at the maternal-fetal interface during late… read more here.
Keywords: immune cells; slpi; secretion; antileukoproteinase ... See more keywords
Daikenchuto, a Japanese herbal medicine, ameliorates experimental colitis in a murine model by inducing secretory leukocyte protease inhibitor and modulating the gut microbiota
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1457562
Abstract: Background Inflammatory bowel disease (IBD) is a refractory inflammatory disorder of the intestine, which is probably triggered by dysfunction of the intestinal epithelial barrier. Secretory leukocyte protease inhibitor (SLPI) secreted by colon epithelial cells protects… read more here.
Keywords: mice; gut microbiota; medicine; protease ... See more keywords
Tonsillar swabs and sputum predict SLPI- and AnxA2 expression in tonsils: A prospective study on smoking dependent SLPI- and AnxA2-expression, and tonsillar HPV infection.
Sign Up to like & getrecommendations! Published in 2022 at "Oncology letters"
DOI: 10.3892/ol.2022.13284
Abstract: Previous retrospective studies have elucidated a correlation between secretory leucocyte protease inhibitor (SLPI) and Annexin A2 (AnxA2), patient smoking status and tonsillar human papilloma virus (HPV) status. The current study assessed these parameters prospectively and… read more here.
Keywords: slpi; hpv; expression; slpi anxa2 ... See more keywords
SLPI suppresses hepatocellular carcinoma progression via endoplasmic reticulum stress induced apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.65676
Abstract: Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. Secretory leukocyte protease inhibitor (SLPI) has been reported to function as a regulatory factor in several cancers. However, its biological functions and underlying mechanisms… read more here.
Keywords: progression via; stress; hepatocellular carcinoma; apoptosis ... See more keywords