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Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109879
Abstract: SLX4/FANCP is a key Fanconi anemia (FA) protein and a DNA repair scaffold for incision around a DNA interstrand crosslink (ICL) by its partner XPF nuclease. The tandem UBZ4 ubiquitin-binding domains of SLX4 are critical…
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Keywords:
dna;
slx4;
rnf168 ligase;
recruitment slx4 ... See more keywords
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Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119556
Abstract: OBJECTIVE Poly(ADP-ribose) polymerase-1 (PARP1) interacts and poly(ADP-ribosyl)ates telomere repeat binding factor 2 (TRF2), which acts as a platform to recruit a large number of proteins at the telomere. Since the discovery of TRF2-SLX4 interaction, SLX4…
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Keywords:
telomere localization;
slx4;
telomere length;
u2os cells ... See more keywords