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   Articles with "smac" as a keyword



Molecular basis of SMAC-XIAP binding and the effect of electrostatic polarization

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recommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"

DOI: 10.1080/07391102.2020.1713892

Abstract: Abstract X-chromosome-linked inhibitor of apoptosis (XIAP) inhibits cell apoptosis. Overexpression of XIAP is widely found in human cancers. Second mitochondria-derived activator of caspase (SMAC) protein inhibits XIAP through binding with Baculovirus Inhibitor of apoptosis protein… read more here.

Keywords: protein; xiap binding; xiap; electrostatic polarization ... See more keywords

Downregulation of Smac attenuates H2O2-induced apoptosis via endoplasmic reticulum stress in human lens epithelial cells

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recommendations! Published in 2017 at "Medicine"

DOI: 10.1097/md.0000000000007419

Abstract: Background: Second mitochondria-derived activator of caspases (Smac) is reported to promote apoptosis. Given the important role of apoptosis in cataract development, the aim of this study was to investigate whether Smac induces human lens epithelial… read more here.

Keywords: endoplasmic reticulum; apoptosis; induced apoptosis; h2o2 induced ... See more keywords

Integrated OVMD-BiGRU-SMAC Framework for Forecasting Construction Accidents in the Kingdom of Saudi Arabia

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recommendations! Published in 2025 at "IEEE Access"

DOI: 10.1109/access.2025.3589024

Abstract: Construction Accidents (CA) remain a major concern for occupational safety, especially within high-risk environments such as those found across the expanding construction sector in the Kingdom of Saudi Arabia (KSA). This research introduces an innovative… read more here.

Keywords: framework; bigru; smac; kingdom saudi ... See more keywords

A Novel Aerosol Retrieval Method Based on Joint Polarization and Intensity Data of Synchronization Monitoring Atmospheric Corrector (SMAC) Onboard High-Spatial-Resolution GFDM Satellite

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recommendations! Published in 2025 at "IEEE Transactions on Geoscience and Remote Sensing"

DOI: 10.1109/tgrs.2025.3549452

Abstract: Synchronization monitoring atmospheric corrector (SMAC) sensor is equipped with polarization and intensity data, providing the possibility of retrieving more accurate aerosol parameters for main sensor’s atmospheric correction. In this study, a novel aerosol retrieval algorithm… read more here.

Keywords: polarization; smac; intensity; aerosol retrieval ... See more keywords

Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6

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recommendations! Published in 2023 at "Science"

DOI: 10.1126/science.ade8840

Abstract: Certain inhibitor of apoptosis (IAP) family members are sentinel proteins that prevent untimely cell death by inhibiting caspases. Antagonists, including second mitochondria-derived activator of caspases (SMAC), regulate IAPs and drive cell death. Baculoviral IAP repeat-containing… read more here.

Keywords: cell death; smac; ubiquitin ligase; birc6 ... See more keywords