Single-Molecule Multikilobase-Scale Profiling of Chromatin Accessibility Using m6A-SMAC-Seq and m6A-CpG-GpC-SMAC-Seq.
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DOI: 10.1007/978-1-0716-2140-0_15
Abstract: A hallmark feature of active cis-regulatory elements (CREs) in eukaryotes is their nucleosomal depletion and, accordingly, higher accessibility to enzymatic treatment. This property has been the basis of a number of sequencing-based assays for genome-wide… read more here.
Keywords: chromatin accessibility; smac seq; single molecule; seq ... See more keywords