Articles with "smad2 phosphorylation" as a keyword



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Smad2/3 phosphorylation is down-regulated in T cells in HIV-infected patients.

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Published in 2022 at "AIDS research and human retroviruses"

DOI: 10.1089/aid.2021.0212

Abstract: Persistent inflammation contributes to the exhaustion of immune system and non-AIDS-defining events in HIV-infected patients. Transforming growth factor β (TGF-β) is generally considered an anti-inflammatory cytokine. It is unclear that why high-level TGF-β coexists with… read more here.

Keywords: regulated cells; phosphorylation regulated; hiv infected; infected patients ... See more keywords
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Sustained Smad2 Phosphorylation Is Required for Myofibroblast Transformation in Response to TGF-β.

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Published in 2019 at "American journal of respiratory cell and molecular biology"

DOI: 10.1165/rcmb.2018-0252le

Abstract: Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal disease characterized by parenchymal fibrosis and structural distortion of the lungs. IPF is believed to be a disorder of abnormal wound healing, wherein the initial trigger to… read more here.

Keywords: response tgf; tgf; phosphorylation; sustained smad2 ... See more keywords

TGF-β induces Smad2 Phosphorylation, ARE Induction, and Trophoblast Differentiation

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Published in 2018 at "International Journal of Stem Cells"

DOI: 10.15283/ijsc17069

Abstract: Background Transforming growth factor beta (TGF-β) signaling has been shown to control a large number of critical cellular actions such as cell death, differentiation, and development and has been implicated as a major regulator of… read more here.

Keywords: trophoblast differentiation; sm10; tgf; differentiation ... See more keywords