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2
Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30823
Abstract: The adipose‐derived stromal vascular fraction (SVF) is composed of a heterogeneous mix of adipose‐derived stem cells (ADSCs), macrophages, pericytes, fibroblasts, blood, and other cells. Previous studies have found that the paracrine effects of SVF cells…
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Keywords:
effect;
stromal vascular;
expression;
vascular fraction ... See more keywords
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2
Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23552
Abstract: Ochratoxin A (OTA) is a mycotoxin generated by Penicillium and Aspergillus species. It is often found in cereals. We hypothesized that OTA exposure induces epithelial–mesenchymal transition (EMT), leading to liver fibrosis. In this research, we…
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Keywords:
tgf receptor;
hepatic fibrosis;
smad2 signaling;
tgf ... See more keywords
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1
Published in 2020 at "International Journal of Endocrinology"
DOI: 10.1155/2020/3260728
Abstract: Objective To explore the role and mechanism of BKCa in diabetic kidney disease. Methods Rat mesangial cells (MCs) HBZY-1 were cultured with high glucose to simulate the high-glucose environment of diabetic kidney disease in vivo.…
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Keywords:
tgf smad2;
high glucose;
smad2 signaling;
cell ... See more keywords
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2
Published in 2023 at "JCI Insight"
DOI: 10.1172/jci.insight.166688
Abstract: TGF-β signaling is crucial for modulating osteoarthritis (OA), and protein phosphatase magnesium–dependent 1A (PPM1A) has been reported as a phosphatase of SMAD2 and regulates TGF-β signaling, while the role of PPM1A in cartilage homeostasis and…
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Keywords:
smad2;
tgf smad2;
smad2 signaling;
protein phosphatase ... See more keywords
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1
Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.769717
Abstract: Stroke is a disease with high morbidity, disability and mortality, which seriously endangers the life span and quality of life of people worldwide. Angiogenesis and neuroprotection are the key to the functional recovery of penumbra…
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Keywords:
signaling pathway;
smad2;
tgf smad2;
smad2 signaling ... See more keywords
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2
Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.900205
Abstract: Introduction: Nanofat is an effective cell therapy for osteoarthritis (OA). However, it has clinical limitations due to its short half-life. We developed Nanofat lysate (NFL) to overcome the defect of Nanofat and explore its anti-OA…
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Keywords:
nanofat lysate;
osteoarthritis;
smad2;
tgf smad2 ... See more keywords
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1
Published in 2022 at "Toxics"
DOI: 10.3390/toxics10050274
Abstract: Recent studies indicated renal toxicity and interstitial nephritis in patients receiving leflunomide (LEFN), but the exact mechanism is still unknown. The transforming growth factor β (TGFβ)/p53/Smad2/3 pathway crucially mediates renal fibrosis. We aimed to assess…
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Keywords:
smad2 signaling;
p53 smad2;
nephrotoxicity mice;
p53 ... See more keywords
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1
Published in 2022 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.3724/abbs.2022076
Abstract: The incidence of endometrial cancer (EC) increases annually and tends to occur in younger women. A particularly important relationship exists between EC and metabolic disorders. As one of the most important components of lipid metabolism,…
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Keywords:
endometrial cancer;
signaling pathway;
lpcat1;
tgf smad2 ... See more keywords
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0
Published in 2022 at "Molecular medicine reports"
DOI: 10.3892/mmr.2022.12782
Abstract: Mangiferin (MAG) is a polyphenolic compound present in mangoes. This compound suppresses inflammation and decreases bone destruction. This study aimed to determine whether MAG directly promotes proliferation and osteogenic differentiation of human periodontal ligament stem…
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Keywords:
osteogenic differentiation;
tgf smad2;
smad2 signaling;
differentiation ... See more keywords