Natural flavonoid pectolinarigenin alleviated kidney fibrosis via inhibiting the activation of TGFβ/SMAD3 and JAK2/STAT3 signaling.
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DOI: 10.1016/j.intimp.2020.107279
Abstract: Renal fibrosis is a final common manifestation of CKD resulting in progressive loss of kidney function. The activation of SMAD3 and STAT3 played central roles in the pathogenesis of renal fibrosis, which has been recognized… read more here.
Keywords: fibrosis; smad3; tgf; activation ... See more keywords