The small acid-soluble proteins of Clostridioides difficile are important for UV resistance and serve as a check point for sporulation
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1009516
Abstract: Clostridioides difficile is a nosocomial pathogen which causes severe diarrhea and colonic inflammation. C. difficile causes disease in susceptible patients when endospores germinate into the toxin-producing vegetative form. The action of these toxins results in… read more here.
Keywords: small acid; sasps; clostridioides difficile; resistance ... See more keywords
The small acid-soluble proteins of Clostridioides difficile regulate sporulation in a SpoIVB2-dependent manner
Sign Up to like & getrecommendations! Published in 2024 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1012507
Abstract: Clostridioides difficile is a pathogen whose transmission relies on the formation of dormant endospores. Spores are highly resilient forms of bacteria that resist environmental and chemical insults. In recent work, we found that C. difficile… read more here.
Keywords: sporulation; small acid; clostridioides difficile; acid soluble ... See more keywords