Paired CT Measures of Emphysema and Small Airways Disease and Lung Function and Exercise Capacity in Smokers with Radiographic Bronchiectasis.
Sign Up to like & getrecommendations! Published in 2020 at "Academic radiology"
DOI: 10.1016/j.acra.2020.02.013
Abstract: RATIONALE AND OBJECTIVES Bronchiectasis (BE) is associated with chronic obstructive pulmonary disease (COPD), but emphysema and small airways disease, main pathologic features of COPD, have been sparsely studied in BE. We aimed to objectively assess… read more here.
Keywords: small airways; exercise capacity; emphysema small; disease ... See more keywords
Multi-resolution classification of exhaled aerosol images to detect obstructive lung diseases in small airways
Sign Up to like & getrecommendations! Published in 2017 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2017.05.019
Abstract: Exhaled aerosol patterns have been used to detect obstructive respiratory diseases in the upper airways. Signals from small airway diseases are weak and may not manifest themselves in the exhaled aerosol patterns. Therefore, it will… read more here.
Keywords: small airways; resolution; classification; exhaled aerosol ... See more keywords
Small airways and airspace inflammation and injury distinguish lung histopathology in deployed military personnel from healthy and diseased lungs.
Sign Up to like & getrecommendations! Published in 2022 at "Human pathology"
DOI: 10.1016/j.humpath.2022.02.014
Abstract: The link between military deployment to Southwest Asia and Afghanistan and risk for lung disease, including bronchiolitis, is increasingly well-recognized. However, histopathologic features that distinguish deployment-related lung diseases from other diseases affecting the small airways… read more here.
Keywords: lung; small airways; inflammation injury; histopathology ... See more keywords
Why We Should Target Small Airways Disease in Our Management of Chronic Obstructive Pulmonary Disease.
Sign Up to like & getrecommendations! Published in 2021 at "Mayo Clinic proceedings"
DOI: 10.1016/j.mayocp.2021.03.016
Abstract: For more than 50 years, small airways disease has been considered a key feature of chronic obstructive pulmonary disease (COPD) and a major cause of airway obstruction. Both preventable and treatable, small airways disease has… read more here.
Keywords: small airways; chronic obstructive; airways disease; obstructive pulmonary ... See more keywords
Small airways' function in Obstructive Sleep Apnea-Hypopnea Syndrome.
Sign Up to like & getrecommendations! Published in 2020 at "Pulmonology"
DOI: 10.1016/j.pulmoe.2020.05.006
Abstract: INTRODUCTION AND OBJECTIVES Most of the studies of the pathophysiology of Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) focus on the collapsibility and obstruction of the upper airways. The aim of our study was the investigation of… read more here.
Keywords: small airways; airways function; apnea hypopnea; obstructive sleep ... See more keywords
Evaluation of the severity of small airways obstruction and alveolar destruction in chronic obstructive pulmonary disease.
Sign Up to like & getrecommendations! Published in 2018 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2018.07.002
Abstract: BACKGROUND Airflow limitation in COPD is caused by a mixture of small airways obstruction and alveolar destruction. OBJECTIVE To evaluate the contributions of these factors to airflow limitation through measurement of two biomarkers, pentosidine and… read more here.
Keywords: small airways; vegf; alveolar destruction; airways obstruction ... See more keywords
Characterising the role of small airways in severe asthma using low frequency forced oscillations: A combined computational and clinical approach.
Sign Up to like & getrecommendations! Published in 2020 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2020.106022
Abstract: BACKGROUND Within asthma, the small airways (≤2 mm in diameter) play an important role in pathophysiology. Using a combined clinical-computational approach, we sought to more precisely evaluate the contribution of the small airways to deep-breath induced… read more here.
Keywords: small airways; severe asthma; bronchial challenge; role ... See more keywords
Direct Visualization and Quantitative Imaging of Small Airway Anatomy Using Deep Learning Assisted Diffractive OCT
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Biomedical Engineering"
DOI: 10.1109/tbme.2022.3188173
Abstract: Objective/background: In vivo imaging and quantification of the microstructures of small airways in three dimensions (3D) allows a better understanding and management of airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD). At… read more here.
Keywords: diffractive oct; small airways; airway anatomy; anatomy ... See more keywords
P225 Comparison of ICS containing open triple and dual therapy on small airways function in the smoking asthma phenotype
Sign Up to like & getrecommendations! Published in 2019 at "Thorax"
DOI: 10.1136/thorax-2019-btsabstracts2019.368
Abstract: Background Patients with asthma who smoke are difficult to manage and are usually excluded from clinical trials. Smoking not only worsens underlying asthma inflammation and airway hyper-responsiveness but also induces resistance to inhaled corticosteroids (ICS).… read more here.
Keywords: small airways; bdp olo; olo tio;
Quantitative Chest CT Assessment of Small Airways Disease in Post-Acute SARS-CoV-2 Infection
Sign Up to like & getrecommendations! Published in 2022 at "Radiology"
DOI: 10.1148/radiol.212170
Abstract: Background The long-term effects of SARS-CoV-2 infection on pulmonary structure and function remain incompletely characterized. Purpose To test whether SARS-CoV-2 infection leads to small airways disease in patients with persistent symptoms. Materials and Methods In… read more here.
Keywords: small airways; infection; airways disease; cov infection ... See more keywords
Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Physiology - Lung Cellular and Molecular Physiology"
DOI: 10.1152/ajplung.00437.2020
Abstract: Lungs of smokers and chronic obstructive pulmonary disease (COPD) are severely compromised and are susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) attack. The dangerous combination of enhanced SARS-CoV-2 attachment receptor protein ACE2 along… read more here.
Keywords: small airways; smokers copd; copd patients; physiology ... See more keywords