Articles with "small chemical" as a keyword



Position of O-Acetylation within the Capsular Repeat Unit Impacts the Biological Properties of Pneumococcal Serotypes 33A and 33F

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Published in 2017 at "Infection and Immunity"

DOI: 10.1128/iai.00132-17

Abstract: ABSTRACT Streptococcus pneumoniae (pneumococcus) produces many capsule types that differ in their abilities to evade host immune recognition. To explain these serotype-dependent protective capacities, many studies have investigated capsular thickness or the interaction of the… read more here.

Keywords: acetylation; small chemical; serotypes 33a; capsule ... See more keywords
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Analysis to determine the effect of mutations on binding to small chemical molecules

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Published in 2022 at "Journal of bioinformatics and computational biology"

DOI: 10.1142/s0219720022400030

Abstract: In this paper, the authors present and describe, in detail, an original software-implemented numerical methodology used to determine the effect of mutations on binding to small chemical molecules, on the example of gefitinib, AMPPNP, CO-1686,… read more here.

Keywords: mutations binding; effect mutations; binding small; small chemical ... See more keywords