Frequency of small-colony variants and antimicrobial susceptibility of methicillin-resistant Staphylococcus aureus in cystic fibrosis patients.
Sign Up to like & getrecommendations! Published in 2018 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2017.11.012
Abstract: BACKGROUND Small-colony variants (SCVs) are a distinct phenotype of Staphylococcus aureus, known for their role in chronic, difficult to treat infections, including cystic fibrosis (CF) lung disease. The goal of this study was to characterize… read more here.
Keywords: small colony; mrsa; scv mrsa; colony variants ... See more keywords
Properties and control of cold-induced small colony variants of Staphylococcus aureus
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DOI: 10.1016/j.fbio.2020.100874
Abstract: Abstract Staphylococcus aureus can survive at low temperature which existed a potential risk of food safety. In this paper, the properties of cold-induced small colony variants (SCVs) were investigated including the antibiotic resistance, biofilm formation… read more here.
Keywords: staphylococcus aureus; cold induced; small colony; induced small ... See more keywords
Novel Bacterial Diversity and Fragmented eDNA Identified in Hyperbiofilm-Forming Pseudomonas aeruginosa Rugose Small Colony Variant
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DOI: 10.1016/j.isci.2020.100827
Abstract: Summary Pseudomonas aeruginosa biofilms represent a major threat to health care. Rugose small colony variants (RSCV) of P. aeruginosa, isolated from chronic infections, display hyperbiofilm phenotype. RSCV biofilms are highly resistant to antibiotics and host… read more here.
Keywords: rugose small; pseudomonas aeruginosa; pao1 wspf; small colony ... See more keywords
Inactivation of genes in oxidative respiration and iron acquisition pathways in pediatric clinical isolates of Small colony variant Enterobacteriaceae
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DOI: 10.1038/s41598-021-86764-4
Abstract: Isolation of bacterial small colony variants (SCVs) from clinical specimens is not uncommon and can fundamentally change the outcome of the associated infections. Bacterial SCVs often emerge with their normal colony phenotype (NCV) co-isolates in… read more here.
Keywords: colony; scv; small colony; iron ... See more keywords
Triclosan-resistant small-colony variants of Staphylococcus aureus produce less capsule, less phenol-soluble modulins, and are attenuated in a Galleria mellonella model of infection
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DOI: 10.1099/mic.0.001277
Abstract: In recent work we identified genes that confer the slow-growing and antibiotic-resistant small-colony variant (SCV) form of Staphylococcus aureus , as associated with the amount of capsule the bacteria produce. In this study we isolated… read more here.
Keywords: triclosan resistant; less capsule; small colony; staphylococcus aureus ... See more keywords
Mutation to ispA Produces Stable Small-Colony Variants of Pseudomonas aeruginosa That Have Enhanced Aminoglycoside Resistance
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DOI: 10.1128/aac.00621-22
Abstract: Pseudomonas aeruginosa is a major pathogen in burn wound infections. We present one of the first reports of small-colony variant (SCV) emergence of P. aeruginosa, taken from a patient under aminoglycosides for a persistent burn… read more here.
Keywords: small colony; mutation; aminoglycoside resistance; pseudomonas aeruginosa ... See more keywords
In Vitro Susceptibility of Clinical Staphylococcus aureus Small-Colony Variants to β-Lactam and Non-β-Lactam Antibiotics
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DOI: 10.1128/aac.02532-17
Abstract: ABSTRACT The Staphylococcus aureus small-colony variant (SCV) phenotype has been associated with relapsing and antibiotic-refractory infections. However, little is known about the activities of antibiotics on clinical SCVs. Here, we demonstrated that SCVs without detectable… read more here.
Keywords: staphylococcus aureus; lactam non; aureus small; lactam antibiotics ... See more keywords
Acute Infection with a Tobramycin-Induced Small Colony Variant of Staphylococcus aureus Causes Increased Inflammation in the Cystic Fibrosis Rat Lung
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DOI: 10.1128/iai.00237-22
Abstract: Cystic fibrosis (CF) disease is characterized by lifelong infections with pathogens such as Staphylococcus aureus, leading to eventual respiratory failure. Small colony variants (SCVs) of S. aureus have been linked to worse clinical outcomes for… read more here.
Keywords: tobramycin; staphylococcus aureus; small colony; colony ... See more keywords
Small Colonies, Bigger Problems? New Evidence That Staphylococcus aureus Small Colony Variants Can Worsen Lung Inflammation in Cystic Fibrosis Rats
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DOI: 10.1128/iai.00413-22
Abstract: Staphylococcus aureus is the most prevalent cystic fibrosis (CF) pathogen. During chronic airway infections, S. aureus adaptation to antibiotics includes evolving small colony variants (SCVs). ABSTRACT Staphylococcus aureus is the most prevalent cystic fibrosis (CF)… read more here.
Keywords: colony variants; staphylococcus aureus; small colony; colony ... See more keywords
MRSA Isolates from Patients with Persistent Bacteremia Generate Nonstable Small Colony Variants In Vitro within Macrophages and Endothelial Cells during Prolonged Vancomycin Exposure
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DOI: 10.1128/iai.00423-22
Abstract: Staphylococcus aureus (especially methicillin-resistant S. aureus [MRSA]) is frequently associated with persistent bacteremia (PB) during vancomycin therapy despite consistent susceptibility in vitro. Strategic comparisons of PB strains versus those from vancomycin-resolving bacteremia (RB) would yield… read more here.
Keywords: persistent bacteremia; vancomycin; within macrophages; small colony ... See more keywords
Heme-Dependent Siderophore Utilization Promotes Iron-Restricted Growth of the Staphylococcus aureus hemB Small-Colony Variant
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bacteriology"
DOI: 10.1128/jb.00458-21
Abstract: S. aureus small-colony variants (SCVs) are associated with chronic recurrent infection and worsened clinical outcome. SCVs persist within the host despite administration of antibiotics. ABSTRACT Respiration-deficient Staphylococcus aureus small-colony variants (SCVs) frequently cause persistent infections,… read more here.
Keywords: growth; siderophore; hemb; small colony ... See more keywords